SCHEMBL6547345

SCHEMBL6547345

CCC(c1ccccc1C)c1ccc(C)cc1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.39
CASR P41180 1/20 0.38
CACNA2D1 P54289 3/20 0.37
CACNA1B Q00975 3/20 0.37
CACNB1 Q02641 3/20 0.37
CACNA1C Q13936 2/20 0.37
CACNA1G O43497 1/20 0.37
CYP2D6 P10635 2/20 0.37
SLC22A2 O15244 1/20 0.37
SLC22A1 O15245 1/20 0.37
GRIN2D O15399 1/20 0.37
GRIN3B O60391 1/20 0.37
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
CHRM5 P08912 1/20 0.37
ADRA2A P08913 1/20 0.37
CHRM1 P11229 1/20 0.37
ADRA2B P18089 1/20 0.37
CHRM3 P20309 1/20 0.37
DRD1 P21728 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5610781 0.90 TDP1 (0.39) CASRCACNA2D1CACNA1BCACNB1CACNA1C
SCHEMBL6546654 0.87 CACNA2D1 (0.47) ESR1CASRCACNA2D1CACNA1BCACNB1
SCHEMBL6547004 0.86 ESR1 (0.50) ESR1CYP2D6SLC22A2SLC22A1GRIN2D
Ammonia Solution, Strong SCHEMBL6000450 0.84 ESR1 (0.48) ESR1CYP2D6SLC22A2SLC22A1GRIN2D
SCHEMBL6546945 0.79 CASR (0.51) ESR1CASRADRA2ACHRM1ADRA2B
SCHEMBL2350960 0.78 HTR2A (0.50) ESR1CYP2D6SLC22A2SLC22A1GRIN2D
Diethylamine SCHEMBL8172450 0.77 ESR1 (0.42) ESR1CYP2D6SLC22A2SLC22A1GRIN2D
SCHEMBL6546231 0.77 ESR1 (0.42) ESR1CYP2D6SLC22A2SLC22A1GRIN2D
SCHEMBL10492715 0.76 CASP1 (0.41) CYP3A4MEN1MAPTKMT2ACRHR1
SCHEMBL6546848 0.76 ESR1 (0.41) ESR1CYP2D6SLC22A2SLC22A1GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed