Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 2/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11279906 | 0.80 | KCNN4 (0.52) | KCNN4MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL23112981 | 0.75 | KCNN4 (0.43) | KCNN4ALDH1A1L3MBTL1 | |
| SCHEMBL18035826 | 0.75 | ALDH1A1 (0.44) | RAB9ANPC1KCNN4MEN1KMT2A | |
| Biphenyl SCHEMBL7519251 | 0.72 | KCNN4 (0.44) | KCNN4ALDH1A1L3MBTL1LMNA | |
| SCHEMBL14855117 | 0.72 | IDO1 (0.62) | MAPK13MAPK12MAPK11MAPK14RAB9A | |
| SCHEMBL8177 | 0.72 | CES1 (0.40) | RAB9ANPC1KCNN4ALDH1A1L3MBTL1 | |
| SCHEMBL574740 | 0.71 | CA1 (0.57) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL874147 | 0.71 | KCNN4 (0.43) | KCNN4ALDH1A1VNN1HDAC3HDAC4 | |
| SCHEMBL7535593 | 0.71 | KCNN4 (0.39) | RAB9AKCNN4MEN1KMT2AALDH1A1 | |
| SCHEMBL11586969 | 0.71 | AKR1B1 (0.53) | RAB9AMEN1KMT2AALDH1A1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119657-B2 | Enantiomeric compositions of 2-amino-1-(2-isopropylpyrazolo[1,5-α]pyridin-3-yl)propan-1-one and related methods | MEDICINOVA, INC. (US) | 2012-02-21 | — | — | US | disclosed |