SCHEMBL6547208

SCHEMBL6547208

Cc1ccccc1CC(C)c1ccccc1C

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.43
TAAR1 Q96RJ0 1/20 0.42
NR3C2 P08235 2/20 0.40
NR3C1 P04150 1/20 0.39
PGR P06401 1/20 0.39
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
SLC6A3 Q01959 1/20 0.37
KCNH2 Q12809 1/20 0.37
TSHR P16473 2/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
CHRM2 P08172 2/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6546356 0.86 NR3C2 (0.42) ESR1TAAR1NR3C2NR3C1PGR
SCHEMBL6546229 0.86 ADRA2A (0.39) ESR1TAAR1NR3C2NR3C1PGR
SCHEMBL1954000 0.85 TSHR (0.48) ESR1NR3C2CYP2D6TSHR
SCHEMBL2024847 0.85 TSHR (0.58) TAAR1TSHRPPARGPPARA
SCHEMBL6546230 0.83 NR3C1 (0.43) TAAR1NR3C2NR3C1PGRSLC6A2
SCHEMBL9318564 0.81 ESR1 (0.45) ESR1TAAR1SLC6A2SLC6A4CYP3A4
SCHEMBL6547400 0.80 TAAR1 (0.48) ESR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL1838330 0.79 TSHR (0.43) TAAR1TSHR
SCHEMBL1954893 0.79 TSHR (0.43) ESR1NR3C2TSHR
SCHEMBL6547026 0.79 SLC6A2 (0.49) TAAR1SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed
EP-0206699-B1 SOLVENT FOR CHROMOGENIC DYE-PRECURSORS FOR PRESSURE-SENSITIVE RECORDING PAPERS KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-04-11 EP disclosed
US-4786630-A MIXTURE OF 1-TOLYL-2-PHENYLPROPANE AND 1,2-DITOLYLETHANE KUREHA KAGAKU KOGYO KABUSHIKI KAISHI (JP) 1988-11-22 US disclosed
US-4737189-A MIXED REACTION PRODUCT OF COUPLING ETHYLBENZENE AND XYLENE Kawaguti & Partners (JP) 1988-04-12 US disclosed
EP-0206699-A1 Solvent for chromogenic dye-precursors for pressure-sensitive recording papers KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1986-12-30 EP disclosed