Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | FURIN | P09958 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11657213 | 1.00 | PRCP (0.42) | PRCPDPP7FURINKEAP1HDAC3 | |
| SCHEMBL11174438 | 1.00 | PRCP (0.42) | PRCPDPP7FURINKEAP1HDAC3 | |
| SCHEMBL29924267 | 0.93 | PRCP (0.41) | PRCPDPP7FURINKEAP1HDAC3 | |
| SCHEMBL29548137 | 0.93 | PRCP (0.41) | PRCPDPP7FURINKEAP1HDAC3 | |
| SCHEMBL29630736 | 0.89 | KEAP1 (0.39) | PRCPDPP7FURINKEAP1HDAC3 | |
| SCHEMBL29808626 | 0.88 | PRCP (0.46) | PRCPDPP7FURINMEN1KMT2A | |
| SCHEMBL30974174 | 0.87 | KDM1A (0.38) | PRCPDPP7FURINKEAP1HDAC3 | |
| SCHEMBL29496543 | 0.87 | MEN1 (0.44) | PRCPDPP7FURINKEAP1HDAC3 | |
| SCHEMBL8468595 | 0.87 | KEAP1 (0.35) | PRCPDPP7FURINKEAP1HDAC3 | |
| SCHEMBL17711236 | 0.86 | MEN1 (0.47) | PRCPDPP7FURINMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759772-B1 | TRI-, TETRA-, PENTA-, AND POLYPEPTIDES AND THEIR THERAPEUTIC USE AS AN ANTIDEPRESSANT AGENT | INNAPHARMA INC (US) | 2004-01-21 | — | — | EP | claimed |
| EP-0759772-A4 | TRI-, TETRA-, PENTA-, AND POLYPEPTIDES AND THEIR THERAPEUTIC USE AS AN ANTIDEPRESSANT AGENT | INNAPHARMA INC (US) | 1999-04-21 | — | — | EP | claimed |
| EP-0759772-A1 | TRI-, TETRA-, PENTA-, AND POLYPEPTIDES AND THEIR THERAPEUTIC USE AS AN ANTIDEPRESSANT AGENT | INNAPHARMA, INC. (US) | 1997-03-05 | — | — | EP | claimed |
| WO-1995030430-A1 | TRI-, TETRA-, PENTA-, AND POLYPEPTIDES AND THEIR THERAPEUTIC USE AS AN ANTIDEPRESSANT AGENT | INNAPHARMA, INC. (US) | 1995-11-16 | — | — | WO | claimed |