Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | FURIN | P09958 | 3/20 | 0.34 |
| ▸ | PRCP | P42785 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 3/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11657213 | 0.87 | PRCP (0.42) | KEAP1FURINPRCPDPP7MAPK8 | |
| SCHEMBL11174438 | 0.87 | PRCP (0.42) | KEAP1FURINPRCPDPP7MAPK8 | |
| SCHEMBL6547215 | 0.87 | PRCP (0.42) | KEAP1FURINPRCPDPP7MAPK8 | |
| SCHEMBL29548137 | 0.80 | PRCP (0.41) | KEAP1FURINPRCPDPP7HDAC3 | |
| SCHEMBL29924267 | 0.80 | PRCP (0.41) | KEAP1FURINPRCPDPP7HDAC3 | |
| SCHEMBL29630736 | 0.77 | KEAP1 (0.39) | KEAP1FURINPRCPDPP7MAPK8 | |
| SCHEMBL29808626 | 0.76 | PRCP (0.46) | FURINPRCPDPP7KDM1A | |
| SCHEMBL30974174 | 0.76 | KDM1A (0.38) | KEAP1FURINPRCPDPP7KDM1A | |
| SCHEMBL29980620 | 0.76 | PRCP (0.39) | KEAP1FURINPRCPDPP7MAPK8 | |
| SCHEMBL29496543 | 0.76 | MEN1 (0.44) | KEAP1FURINPRCPDPP7KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759772-A4 | TRI-, TETRA-, PENTA-, AND POLYPEPTIDES AND THEIR THERAPEUTIC USE AS AN ANTIDEPRESSANT AGENT | INNAPHARMA INC (US) | 1999-04-21 | — | — | EP | claimed |
| EP-0759772-A1 | TRI-, TETRA-, PENTA-, AND POLYPEPTIDES AND THEIR THERAPEUTIC USE AS AN ANTIDEPRESSANT AGENT | INNAPHARMA, INC. (US) | 1997-03-05 | — | — | EP | claimed |
| WO-1995030430-A1 | TRI-, TETRA-, PENTA-, AND POLYPEPTIDES AND THEIR THERAPEUTIC USE AS AN ANTIDEPRESSANT AGENT | INNAPHARMA, INC. (US) | 1995-11-16 | — | — | WO | claimed |
| WO-1999022758-A1 | TRI-, TETRA-, PENTA-, AND POLYPEPTIDES AND THEIR THERAPEUTIC USE AS AN ANTIDEPRESSANT AGENT | INNAPHARMA, INC. (US) | 1999-05-14 | — | — | WO | disclosed |