Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ADAM33 | Q9BZ11 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6549283 | 0.85 | SMN1; SMN2 (0.45) | KMT2AMEN1NPSR1LMNAALDH1A1 | |
| SCHEMBL6547904 | 0.78 | MEN1 (0.48) | KMT2AMEN1NPSR1LMNAALDH1A1 | |
| SCHEMBL6547247 | 0.78 | KMT2A (0.54) | KMT2AMEN1NPSR1LMNAALDH1A1 | |
| SCHEMBL6549109 | 0.74 | LMNA (0.44) | KMT2ALMNAALDH1A1TSHRPOLB | |
| SCHEMBL27471335 | 0.73 | KMT2A (0.50) | KMT2AMEN1NPSR1LMNAALDH1A1 | |
| SCHEMBL6549050 | 0.72 | KMT2A (0.54) | KMT2AMEN1NPSR1LMNAALDH1A1 | |
| SCHEMBL12027622 | 0.69 | MEN1 (0.59) | KMT2AMEN1NPSR1LMNAALDH1A1 | |
| SCHEMBL22648518 | 0.69 | MEN1 (0.59) | KMT2AMEN1NPSR1LMNAALDH1A1 | |
| SCHEMBL13049037 | 0.69 | MEN1 (0.59) | KMT2AMEN1NPSR1LMNAALDH1A1 | |
| SCHEMBL7349999 | 0.69 | MEN1 (0.56) | KMT2AMEN1NPSR1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1106609-B1 | Aminoalcohol derivative and medicament comprising the same | SEIKAGAKU KOGYO CO LTD (JP) | 2004-12-01 | — | — | EP | disclosed |
| US-6407064-B2 | A MORPHOLINO RING CONTAINING ALKYLAMINOALCOHOL DERIVATIVE OR SALTS USEFUL FOR TREATING NEURONAL DISEASES AND AN AGENT FOR PROTECTING BRAIN | SEIKAGAKU CORPORATION (JP) | 2002-06-18 | — | — | US | disclosed |
| US-20010003741-A1 | Aminoalcohol derivative and medicament comprising the same | SEIKAGAKU CORPORATION (JP) | 2001-06-14 | — | — | US | disclosed |
| EP-1106609-A2 | Aminoalcohol derivative and medicament comprising the same | SEIKAGAKU CORPORATION (JP) | 2001-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010003741-A1 | Aminoalcohol derivative and medicament comprising the same | SGMS2, FABP7, SGMS1 | KMT2A 2489/4885MEN1 2933/4885NPSR1 2237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.