SCHEMBL6547263

SCHEMBL6547263

FC(F)(F)c1ccc(CON=CCCCCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.34
MAPT P10636 2/20 0.34
KMT2A Q03164 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
PSMD14 O00487 1/20 0.34
ALDH1A1 P00352 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
PPARG P37231 3/20 0.33
PPARD Q03181 2/20 0.33
PPARA Q07869 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
NR1I3 Q14994 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
CYP2C19 P33261 1/20 0.31
MAOB P27338 6/20 0.31
ADCYAP1R1 P41586 1/20 0.31
PTGES O14684 1/20 0.31
ALOX5 P09917 1/20 0.31
PSEN1 P49768 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6547257 1.00 MEN1 (0.34) MEN1MAPTKMT2ATDP1PSMD14
SCHEMBL6550037 0.87 PTGIR (0.34) MEN1MAPTKMT2ATDP1ALDH1A1
SCHEMBL6550031 0.87 PTGIR (0.34) MEN1MAPTKMT2ATDP1ALDH1A1
SCHEMBL6548111 0.87 TDP1 (0.33) MEN1MAPTKMT2ATDP1PPARG
SCHEMBL6548107 0.87 TDP1 (0.33) MEN1MAPTKMT2ATDP1PPARG
SCHEMBL6549194 0.85
SCHEMBL6549198 0.85
SCHEMBL6547103 0.84 PTGIR (0.33) MEN1MAPTKMT2ATDP1ALDH1A1
SCHEMBL6547098 0.84 PTGIR (0.33) MEN1MAPTKMT2ATDP1ALDH1A1
SCHEMBL8655461 0.83 HDAC1 (0.36) MEN1KMT2APPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 MEN1 4425/4885MAPT 4623/4885KMT2A 2985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.