SCHEMBL6548111

SCHEMBL6548111

COc1ccc(CON=CCCCCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPT P10636 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
CYP1A2 P05177 1/20 0.32
PKM P14618 1/20 0.32
HTT P42858 1/20 0.32
FFAR1 O14842 1/20 0.31
PPARG P37231 1/20 0.31
PPARD Q03181 1/20 0.31
PPARA Q07869 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
NR1I3 Q14994 1/20 0.31
TNFRSF1A P19438 1/20 0.31
KDM4E B2RXH2 2/20 0.30
POLB P06746 1/20 0.30
APP P05067 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6548107 1.00 TDP1 (0.33) TDP1L3MBTL1MEN1KMT2AMAPT
SCHEMBL6550031 0.89 PTGIR (0.34) TDP1L3MBTL1MEN1KMT2AMAPT
SCHEMBL6550037 0.89 PTGIR (0.34) TDP1L3MBTL1MEN1KMT2AMAPT
SCHEMBL6547263 0.87 MEN1 (0.34) TDP1L3MBTL1MEN1KMT2AMAPT
SCHEMBL6547257 0.87 MEN1 (0.34) TDP1L3MBTL1MEN1KMT2AMAPT
SCHEMBL6547103 0.86 PTGIR (0.33) TDP1L3MBTL1MEN1KMT2AMAPT
SCHEMBL6547098 0.86 PTGIR (0.33) TDP1L3MBTL1MEN1KMT2AMAPT
SCHEMBL6548393 0.84 HTT (0.31) HTT
SCHEMBL6548388 0.84 HTT (0.31) HTT
SCHEMBL6547086 0.83 HTT (0.30) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 TDP1 2528/4885L3MBTL1 876/4885MEN1 4425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.