SCHEMBL6547293

SCHEMBL6547293

Sc1nccs1.Sn1cnc2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.39
HTT P42858 3/20 0.38
POLB P06746 1/20 0.38
TNF P01375 1/20 0.35
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
FGFR1 P11362 1/20 0.34
ROCK1 Q13464 1/20 0.34
MKNK1 Q9BUB5 1/20 0.34
MKNK2 Q9HBH9 1/20 0.34
LMNA P02545 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MEN1 O00255 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PDE10A Q9Y233 1/20 0.33
STAT6 P42226 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29600079 0.81 TDP1 (0.54) TDP1HTTPOLBTNFCYP11B1
SCHEMBL39078 0.81 TDP1 (0.54) TDP1HTTPOLBTNFCYP11B1
SCHEMBL5870841 0.79 TDP1 (0.52) TDP1HTTPOLBTNFCYP11B1
SCHEMBL8895778 0.79 TDP1 (0.52) TDP1HTTPOLBTNFCYP11B1
SCHEMBL2504303 0.79 TDP1 (0.52) TDP1HTTPOLBTNFCYP11B1
Hydrogen Sulfide SCHEMBL21496237 0.79 TDP1 (0.52) TDP1HTTPOLBTNFCYP11B1
SCHEMBL11759895 0.79 TDP1 (0.52) TDP1HTTPOLBTNFCYP11B1
2-Mercaptobenzothiazole SCHEMBL8776088 0.74 MGLL (0.38) TDP1HTTPOLBTNFCYP11B1
SCHEMBL8060616 0.71 TDP1 (0.38) TDP1HTTPOLBTNFCYP11B1
SCHEMBL23753 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0929840-B1 SILVER HALIDE LIGHT SENSITIVE EMULSION LAYER HAVING ENHANCED PHOTOGRAPHIC SENSITIVITY EASTMAN KODAK CO (US) 2004-02-18 EP disclosed
EP-0893731-B1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK CO (US) 2004-01-28 EP disclosed
US-6306570-B1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY 2001-10-23 US disclosed
US-6054260-A Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY (US) 2000-04-25 US disclosed
EP-0786690-B1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK CO (US) 2000-03-22 EP disclosed
US-5994051-A DEPROTONATION WITH A BASE TO GIVE FREE RADICALS EASTMAN KODAK COMPANY (US) 1999-11-30 US disclosed
EP-0929840-A1 SILVER HALIDE LIGHT SENSITIVE EMULSION LAYER HAVING ENHANCED PHOTOGRAPHIC SENSITIVITY EASTMAN KODAK COMPANY (US) 1999-07-21 EP disclosed
WO-1999005570-A1 SILVER HALIDE LIGHT SENSITIVE EMULSION LAYER HAVING ENHANCED PHOTOGRAPHIC SENSITIVITY EASTMAN KODAK COMPANY (US) 1999-02-04 WO disclosed
EP-0893731-A1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY (US) 1999-01-27 EP disclosed
US-5747235-A SILVER HALIDE ADSORBERS IN EMULSIONS FOR PHOTOGRAPHIC FILMS EASTMAN KODAK COMPANY (US) 1998-05-05 US disclosed
EP-0786690-A2 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY (US) 1997-07-30 EP disclosed