SCHEMBL5870841

SCHEMBL5870841

Sn1cnc2ccccc21.[Ag]

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.52
HTT P42858 4/20 0.50
CYP11B1 P15538 3/20 0.46
CYP11B2 P19099 3/20 0.46
POLB P06746 1/20 0.46
TNF P01375 1/20 0.46
FGFR1 P11362 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.43
LMNA P02545 2/20 0.43
MEN1 O00255 1/20 0.43
HPGD P15428 1/20 0.43
KMT2A Q03164 1/20 0.43
HSD17B10 Q99714 1/20 0.43
STAT6 P42226 1/20 0.43
MAPK1 P28482 1/20 0.42
EGLN3 Q9H6Z9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39078 0.98 TDP1 (0.54) TDP1HTTCYP11B1CYP11B2POLB
SCHEMBL29600079 0.98 TDP1 (0.54) TDP1HTTCYP11B1CYP11B2POLB
SCHEMBL2504303 0.95 TDP1 (0.52) TDP1HTTCYP11B1CYP11B2POLB
Hydrogen Sulfide SCHEMBL21496237 0.95 TDP1 (0.52) TDP1HTTCYP11B1CYP11B2POLB
SCHEMBL11759895 0.95 TDP1 (0.52) TDP1HTTCYP11B1CYP11B2POLB
SCHEMBL8895778 0.95 TDP1 (0.52) TDP1HTTCYP11B1CYP11B2POLB
SCHEMBL6547293 0.79 TDP1 (0.39) TDP1HTTCYP11B1CYP11B2POLB
SCHEMBL8060616 0.78 TDP1 (0.38) TDP1HTTCYP11B1CYP11B2POLB
2-Mercaptobenzothiazole SCHEMBL8776088 0.78 MGLL (0.38) TDP1HTTCYP11B1CYP11B2POLB
SCHEMBL7196401 0.73 TDP1 (0.58) TDP1HTTCYP11B1CYP11B2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7129021-B2 Polymer system with switchable physical properties and its use in direct exposure printing plates CREO SRL (BB) 2006-10-31 US disclosed
US-20040081911-A1 Polymer system with switchable physical properties and its use in direct exposure printing plates CREO SRL (CA) 2004-04-29 US disclosed
US-4237213-A THERMOGRAPHY; PHOTOSENSITIVE MATERIAL CONTAINING ORGANIC SILVER SALT, HALIDE, AND BINDER CANON KABUSHIKI KAISHA (JP) 1980-12-02 US disclosed