SCHEMBL6547343

SCHEMBL6547343

Cc1ccc(CCCc2ccccc2C)c(C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.50
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
LMNA P02545 1/20 0.41
HTT P42858 1/20 0.41
TNF P01375 1/20 0.41
NPC1 O15118 1/20 0.41
DAO P14920 1/20 0.40
MAPT P10636 1/20 0.40
CHRM2 P08172 1/20 0.39
PYCR1 P32322 1/20 0.39
GPR84 Q9NQS5 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6547470 0.92 TAAR1 (0.54) TAAR1CA12CA1CA2CA7
SCHEMBL6546881 0.85 TAAR1 (0.65) TAAR1CA12CA1CA2CA7
SCHEMBL6546810 0.85 RAB9A (0.50) RAB9ASMN1; SMN2LMNAHTTNPC1
SCHEMBL11323610 0.83 TAAR1 (0.43) TAAR1RAB9ASMN1; SMN2LMNAHTT
SCHEMBL6547356 0.81 RAB9A (0.50) RAB9ASMN1; SMN2LMNAHTTNPC1
SCHEMBL6547406 0.80 TAAR1 (0.48) TAAR1RAB9ASMN1; SMN2LMNAHTT
SCHEMBL6546757 0.80 TAAR1 (0.65) TAAR1CA12CA1CA2CA7
SCHEMBL27472295 0.80 TAAR1 (0.50) TAAR1CA12CA1CA2CA7
SCHEMBL10360566 0.80 IGF1R (0.47) TAAR1RAB9ASMN1; SMN2NPC1PYCR1
SCHEMBL6547395 0.80 RAB9A (0.44) TAAR1RAB9ASMN1; SMN2LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed