SCHEMBL6547356

SCHEMBL6547356

Cc1ccc(CCCCc2ccccc2)c(C)c1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.50
NPC1 O15118 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
TDP1 Q9NUW8 1/20 0.47
HDAC6 Q9UBN7 1/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
POLB P06746 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
MAOA P21397 1/20 0.44
LMNA P02545 2/20 0.43
GAA P10253 1/20 0.43
ALDH1A1 P00352 1/20 0.43
ALOX12 P18054 1/20 0.43
SIGMAR1 Q99720 2/20 0.43
MAOB P27338 1/20 0.42
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6546810 0.96 RAB9A (0.50) RAB9ANPC1SMN1; SMN2TDP1HDAC6
SCHEMBL115910 0.89 RAB9A (0.45) RAB9ANPC1SMN1; SMN2TDP1HDAC6
SCHEMBL30173450 0.89 RAB9A (0.45) RAB9ANPC1SMN1; SMN2TDP1HDAC6
SCHEMBL9614299 0.87 RAB9A (0.44) RAB9ANPC1SMN1; SMN2TDP1HDAC6
SCHEMBL10360566 0.85 IGF1R (0.47) RAB9ANPC1SMN1; SMN2TDP1L3MBTL1
SCHEMBL6547343 0.81 TAAR1 (0.50) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL16010786 0.80 IGF1R (0.45) MEN1KMT2ASIGMAR1MAOB
SCHEMBL7065825 0.79 ESR1 (0.50) RAB9ANPC1SMN1; SMN2HDAC6POLB
SCHEMBL6546802 0.79 TAAR1 (0.52) L3MBTL1MAOAALDH1A1SIGMAR1
SCHEMBL3301748 0.79 CYP3A4 (0.53) RAB9ANPC1SMN1; SMN2LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed