SCHEMBL6547394

SCHEMBL6547394

Cc1ccc(CCC(C)c2ccc(C)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.46
CYP2A6 P11509 1/20 0.46
TAAR1 Q96RJ0 1/20 0.46
ACHE P22303 2/20 0.44
ALDH1A1 P00352 2/20 0.42
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
STAT3 P40763 1/20 0.41
IDO1 P14902 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
DPP4 P27487 1/20 0.39
GRIA4 P48058 1/20 0.39
HRH3 Q9Y5N1 1/20 0.38
KCNH2 Q12809 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ADRB2 P07550 1/20 0.38
BCHE P06276 1/20 0.38
IGF1R P08069 1/20 0.37
ALOX15 P16050 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29291900 0.94 ACHE (0.45) CYP1A2CYP2A6TAAR1ACHEALDH1A1
SCHEMBL6546964 0.90 ALDH1A1 (0.54) CYP1A2ALDH1A1KCNH2SMN1; SMN2ADRB2
SCHEMBL6546640 0.90 ALDH1A1 (0.50) CYP1A2CYP2A6TAAR1ALDH1A1MEN1
SCHEMBL9587937 0.87 ALDH1A1 (0.43) CYP1A2CYP2A6TAAR1ACHEALDH1A1
SCHEMBL24106999 0.85 BCHE (0.39) CYP1A2CYP2A6TAAR1ACHEALDH1A1
SCHEMBL4952650 0.81 TAAR1 (0.50) TAAR1ACHEALDH1A1IDO1MEN1
SCHEMBL10761871 0.81 ESR1 (0.64) CYP1A2ESR1ESR2MEN1KMT2A
SCHEMBL14274070 0.79 ACHE (0.48) TAAR1ACHEESR1ESR2STAT3
SCHEMBL3047188 0.79 CYP1A2 (0.52) CYP1A2CYP2A6TAAR1ACHEALDH1A1
SCHEMBL6547354 0.79 ALDH1A1 (0.48) CYP1A2ALDH1A1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109852443-A A kind of Gasoline octane number enhancer and preparation method thereof 山东聚兴新材料科技有限公司 2019-06-07 CN claimed
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed