Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3074943 | 0.86 | HTT (0.45) | HTTTYRGABRA1GABRB2OPRM1 | |
| SCHEMBL28674805 | 0.86 | HTT (0.45) | HTTTYRGABRA1GABRB2OPRM1 | |
| SCHEMBL29486474 | 0.86 | HTT (0.45) | HTTTYRGABRA1GABRB2OPRM1 | |
| SCHEMBL9621059 | 0.86 | GABRA1 (0.44) | HTTGABRA1GABRB2SLC6A2LMNA | |
| SCHEMBL6547970 | 0.85 | HTT (0.42) | HTTGABRA1GABRB2OPRM1OPRD1 | |
| SCHEMBL6547447 | 0.84 | HTT (0.48) | HTTTYRGABRA1GABRB2OPRM1 | |
| SCHEMBL4657529 | 0.84 | HTT (0.44) | HTTTYRGABRA1GABRB2OPRM1 | |
| SCHEMBL10601615 | 0.83 | HTT (0.43) | HTTTYRGABRA1GABRB2OPRM1 | |
| SCHEMBL10833197 | 0.82 | GABRA1 (0.53) | HTTTYRGABRA1GABRB2OPRM1 | |
| SCHEMBL4658390 | 0.82 | CNR2 (0.43) | TYRSLC6A4SLC6A2TAAR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717098-B1 | A refrigerating machine oil and a fluid composition for use in a refrigerating machine | NIPPON MITSUBISHI OIL CORP (JP) | 2004-01-21 | — | — | EP | disclosed |
| US-5817251-A | AROMATIC HYDROCARBON LUBRICANT | NIPPON OIL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| US-5711895-A | Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group | NIPPON OIL CO., LTD. (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0717098-A2 | A refrigerating machine oil and a fluid composition for use in a refrigerating machine | NIPPON OIL CO. LTD. (JP) | 1996-06-19 | — | — | EP | disclosed |
| US-4347169-A | MIXTURE OF A DIARYLALKANE AND AN ARYLINDANE AND-OR 1,3-DIARYLBUTENE | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1982-08-31 | — | — | US | disclosed |