SCHEMBL6547447

SCHEMBL6547447

CCc1cccc(C(C)c2ccccc2)c1CC

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.48
TYR P14679 1/20 0.39
OPRM1 P35372 1/20 0.37
OPRD1 P41143 1/20 0.37
OPRK1 P41145 1/20 0.37
OPRL1 P41146 1/20 0.37
GABRA1 P14867 3/20 0.36
GABRB2 P47870 2/20 0.36
SLC6A4 P31645 2/20 0.35
SLC6A2 P23975 1/20 0.35
TAAR1 Q96RJ0 2/20 0.34
LMNA P02545 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9448512 0.87 HTT (0.47) HTTGABRA1GABRB2SLC6A4SLC6A2
SCHEMBL11206824 0.87 HTT (0.43) HTTTYROPRM1OPRD1OPRK1
SCHEMBL9621022 0.87 GABRA1 (0.43) HTTGABRA1GABRB2SLC6A2TAAR1
SCHEMBL3074943 0.85 HTT (0.45) HTTTYROPRM1OPRD1OPRK1
SCHEMBL29486474 0.85 HTT (0.45) HTTTYROPRM1OPRD1OPRK1
SCHEMBL28674805 0.85 HTT (0.45) HTTTYROPRM1OPRD1OPRK1
SCHEMBL6547413 0.84 HTT (0.45) HTTTYROPRM1OPRD1OPRK1
SCHEMBL4657529 0.82 HTT (0.44) HTTTYROPRM1OPRD1OPRK1
SCHEMBL11282010 0.82 TYR (0.42) HTTTYROPRM1SLC6A4SLC6A2
SCHEMBL10601615 0.81 HTT (0.43) HTTTYROPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
US-5670704-A TRANSMETHYLATION OF NAPHTHALENE OR 2-METHYLNAPHTHALENE USING LEWIS ACID CATALYST MORE ACIDIC THAN FERRIC CHLORIDE AMOCO CORPORATION (US) 1997-09-23 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed
EP-0487714-A4 SELECTIVE ETHYLATION OF NAPHTHALENE COMPOUNDS 1993-07-07 EP disclosed
US-5210355-A Ethylation of 2-methylnaphthalene with tri-, tetra-, or penta-ethylbenzene in the presence of a catalyst AMOCO CORPORATION (US) 1993-05-11 US disclosed
US-5177286-A Selective production of a p-alkyltoluene or 4,4'-alkylmethylbiphenyl AMOCO CORPORATION (US) 1993-01-05 US disclosed
US-5171917-A Ethylation of benzene, toluene, ethylbenzene or a mixture of benzene and ethylbenzene with 1,2,4-triethylbenezene, tetra- or pentaethylbenzene in the presence of an acid catalys catalyst AMOCO CORPORATION (US) 1992-12-15 US disclosed
EP-0487714-A1 SELECTIVE ETHYLATION OF NAPHTHALENE COMPOUNDS AMOCO CORPORATION (US) 1992-06-03 EP disclosed
WO-1992000260-A1 SELECTIVE ETHYLATION OF NAPHTHALENE COMPOUNDS AMOCO CORPORATION (US) 1992-01-09 WO disclosed
EP-0282064-B1 METHOD FOR PRODUCING M-ETHYLDIPHENYLS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1991-10-23 EP disclosed
US-4835337-A Method for producing m-ethyldiphenyls NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-05-30 US disclosed
EP-0282064-A1 Method for producing m-ethyldiphenyls NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-09-14 EP disclosed
EP-0029645-B1 USE OF DIPHENYLETHANE DERIVATIVE AS SOLVENT FOR COLOUR-FORMER IN PRESSURE-SENSITIVE RECORDING MATERIALS; SOLUTIONS, MICROCAPSULES, SHEETS COATED WITH MICROCAPSULES AND PRESSURE-SENSITIVE RECORDING MATERIALS CONTAINING SAID SOLVENT; METHOD OF COPYING USING SAID SHEETS OR RECORDING MATERIALS KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1983-07-20 EP disclosed
EP-0029645-A2 Use of diphenylethane derivative as solvent for colour-former in pressure-sensitive recording materials; solutions, microcapsules, sheets coated with microcapsules and pressure-sensitive recording materials containing said solvent; method of copying using said sheets or recording materials KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1981-06-03 EP disclosed