Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5074222 | 0.93 | KCNH2 (0.44) | KCNH2SIGMAR1MTNR1AMTNR1BNPC1 | |
| SCHEMBL4970515 | 0.88 | KCNH2 (0.50) | KCNH2SIGMAR1MTNR1AMTNR1BSMPD1 | |
| SCHEMBL10830280 | 0.85 | KCNH2 (0.48) | KCNH2SIGMAR1MTNR1AMTNR1BSMPD1 | |
| SCHEMBL4194250 | 0.85 | KCNH2 (0.48) | KCNH2SIGMAR1MTNR1AMTNR1BSMPD1 | |
| SCHEMBL3637570 | 0.83 | KCNH2 (0.45) | KCNH2SIGMAR1MTNR1AMTNR1BNPC1 | |
| Hydrochloric Acid SCHEMBL10830320 | 0.83 | KCNH2 (0.47) | KCNH2SIGMAR1MTNR1AMTNR1B | |
| SCHEMBL138431 | 0.83 | KCNH2 (0.50) | KCNH2SIGMAR1MTNR1AMTNR1BALDH1A1 | |
| Hydrochloric Acid SCHEMBL11683567 | 0.81 | KCNH2 (0.44) | KCNH2SIGMAR1MTNR1AMTNR1BNPC1 | |
| SCHEMBL7926319 | 0.81 | KCNA3 (0.38) | KCNH2MTNR1AMTNR1B | |
| SCHEMBL9808066 | 0.78 | SIGMAR1 (0.47) | KCNH2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800618-B2 | PHENOTHIAZINE OR IMINODIBENZYL DERIVATIVES AS ANTIMALARIAL AGENTS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2004-10-05 | — | — | US | disclosed |
| US-20040052961-A1 | Electroless copper plating of ferrous metal substrates | CHEMETALL GMBH (DE) | 2004-03-18 | — | — | US | disclosed |
| EP-1381712-A2 | ELECTROLESS COPPER PLATING OF FERROUS METAL SUBSTRATES | Chemetall GmbH (DE) | 2004-01-21 | — | — | EP | disclosed |
| US-20030032801-A1 | Chemosensitizing agents against chloroquine resistant plasmodium falciparum and methods of making and using thereof | U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND | 2003-02-13 | — | — | US | disclosed |
| WO-2002089810-A1 | CHEMOSENSITIZING AGENTS AGAINST CHLOROQUINE RESISTANT PLASMODIUM FALCIPARUM AND METHODS OF MAKING AND USING THEREOF | UNITED STATES ARMY MEDICAL RESEARCH AND MATERIEL COMMAND (US) | 2002-11-14 | — | — | WO | disclosed |
| WO-2002053801-A2 | ELECTROLESS COPPER PLATING OF FERROUS METAL SUBSTRATES | CHEMETALL GMBH (DE) | 2002-07-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030032801-A1 | Chemosensitizing agents against chloroquine resistant plasmodium falciparum and methods of making and using thereof | ABCC1, SLC11A2, G6PD | KCNH2 3044/4885SIGMAR1 174/4885MTNR1A 2570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.