Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5200395 | 0.93 | HTR2A (0.71) | HTR2AHSD11B1ALDH1A1HSD17B10KCNH2 | |
| SCHEMBL11767109 | 0.93 | HTR2A (0.71) | HTR2AHSD11B1ALDH1A1HSD17B10KCNH2 | |
| SCHEMBL9621454 | 0.92 | CA2 (0.50) | HTR2AALDH1A1HPGDHSD17B10CA2 | |
| SCHEMBL6546083 | 0.88 | HTR2A (0.50) | HTR2AALDH1A1HPGDOPRL1KCNH2 | |
| SCHEMBL28900121 | 0.86 | RARB (0.53) | HTR2AHSD11B1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL27497386 | 0.83 | HTR2A (0.48) | HTR2AALDH1A1HPGDHSD17B10CA2 | |
| Butylbenzyl SCHEMBL8519397 | 0.82 | HTR2A (0.53) | HTR2AHSD11B1OPRL1KCNH2SIGMAR1 | |
| SCHEMBL11415015 | 0.80 | TSHR (0.47) | HTR2AALDH1A1HPGDHSD17B10TRPV1 | |
| SCHEMBL8090819 | 0.79 | UCHL3 (0.56) | HTR2AALDH1A1HPGDHSD17B10CA2 | |
| SCHEMBL444227 | 0.79 | TP53 (0.56) | HTR2AALDH1A1OPRL1OPRM1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717098-B1 | A refrigerating machine oil and a fluid composition for use in a refrigerating machine | NIPPON MITSUBISHI OIL CORP (JP) | 2004-01-21 | — | — | EP | disclosed |
| US-5817251-A | AROMATIC HYDROCARBON LUBRICANT | NIPPON OIL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| US-5711895-A | Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group | NIPPON OIL CO., LTD. (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0717098-A2 | A refrigerating machine oil and a fluid composition for use in a refrigerating machine | NIPPON OIL CO. LTD. (JP) | 1996-06-19 | — | — | EP | disclosed |