SCHEMBL6547648

SCHEMBL6547648

CCCC=CC1=CC=CC(C)(c2ccccc2)C1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CXCR5 P32302 2/20 0.34
TLR8 Q9NR97 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6546984 0.81
SCHEMBL27807715 0.70 HDAC9 (0.33)
SCHEMBL6546974 0.70 OPRL1 (0.34)
SCHEMBL28162783 0.66 NPC1 (0.37)
SCHEMBL28794322 0.64 HDAC9 (0.39)
SCHEMBL8206128 0.63 TLR8 (0.51) CXCR5TLR8
SCHEMBL13584113 0.62 TLR8 (0.31) CXCR5TLR8
SCHEMBL78219 0.62 SIGMAR1 (0.53) TLR8
SCHEMBL108128 0.62 SIGMAR1 (0.53) TLR8
SCHEMBL28490848 0.62 SIGMAR1 (0.53) TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed