SCHEMBL6547680

SCHEMBL6547680

ClC(Cl)=CCOc1cc(Cl)c(OCCCCOC/C=N/OCc2ccccc2)c(Cl)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.34
MEN1 O00255 6/20 0.34
KMT2A Q03164 6/20 0.34
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
POLB P06746 1/20 0.34
HTT P42858 1/20 0.34
NPC1 O15118 1/20 0.32
NFKB1 P19838 1/20 0.32
RAB9A P51151 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HTR1A P08908 1/20 0.32
ADRA1D P25100 1/20 0.32
ADRA1A P35348 1/20 0.32
ADRA1B P35368 1/20 0.32
L3MBTL1 Q9Y468 3/20 0.31
HPGD P15428 1/20 0.31
NPY1R P25929 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6547684 1.00 MAPT (0.34) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL6547548 0.99 MAPT (0.33) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL6547541 0.99 MAPT (0.33) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL6550037 0.92 PTGIR (0.34) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL6550031 0.92 PTGIR (0.34) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL6547103 0.91 PTGIR (0.33) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL6547098 0.91 PTGIR (0.33) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL6547855 0.87 KDM4E (0.34) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL6547861 0.87 KDM4E (0.34) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL8011654 0.87 KDM4E (0.30) MAPTMEN1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed
EP-0975586-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION Sumitomo Chemical Company, Limited (JP) 2000-02-02 EP disclosed
WO-1998045254-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 MAPT 4623/4885MEN1 4425/4885KMT2A 2985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.