SCHEMBL6547855

SCHEMBL6547855

CCc1cc(OCC=C(Cl)Cl)cc(CC)c1OCCCCOC/C=N/OCc1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.34
P4HB P07237 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
HTT P42858 2/20 0.32
MAPT P10636 2/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32
KMT2A Q03164 1/20 0.32
PPARG P37231 1/20 0.32
SLC5A2 P31639 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PLA2G2A P14555 1/20 0.30
PLA2G2D Q9UNK4 1/20 0.30
DRD2 P14416 1/20 0.30
DRD3 P35462 1/20 0.30
GLRA1 P23415 1/20 0.30
CNR2 P34972 1/20 0.30
KCNA3 P22001 1/20 0.30
KCNA5 P22460 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6547861 1.00 KDM4E (0.34) KDM4EP4HBNPSR1HTTMAPT
SCHEMBL6549598 0.88 MAOB (0.33) NPSR1MAPTMEN1ALDH1A1KMT2A
SCHEMBL6549596 0.88 MAOB (0.33) NPSR1MAPTMEN1ALDH1A1KMT2A
SCHEMBL6548302 0.88 HTT (0.34) HTT
SCHEMBL6548296 0.88 HTT (0.34) HTT
SCHEMBL6547680 0.87 MAPT (0.34) KDM4EHTTMAPTMEN1ALDH1A1
SCHEMBL6547684 0.87 MAPT (0.34) KDM4EHTTMAPTMEN1ALDH1A1
SCHEMBL6549195 0.87 HTT (0.33) HTT
SCHEMBL6550081 0.87 HTT (0.33) HTT
SCHEMBL6549193 0.87 HTT (0.33) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed
EP-0975586-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION Sumitomo Chemical Company, Limited (JP) 2000-02-02 EP disclosed
WO-1998045254-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 KDM4E 1500/4885P4HB 1046/4885NPSR1 1193/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.