SCHEMBL6547788

SCHEMBL6547788

CCCCOCC=NOCCCCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.33
S1PR2 O95136 1/20 0.33
S1PR1 P21453 1/20 0.33
S1PR3 Q99500 1/20 0.33
LPAR2 Q9HBW0 1/20 0.33
HTT P42858 2/20 0.32
THRA P10827 1/20 0.32
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6547783 1.00 THRB (0.33) THRBS1PR2S1PR1S1PR3LPAR2
SCHEMBL6548079 0.91 HTT (0.31) THRBS1PR2S1PR1S1PR3LPAR2
SCHEMBL6548076 0.91 HTT (0.31) THRBS1PR2S1PR1S1PR3LPAR2
SCHEMBL6548640 0.90 HTT (0.32) HTTMEN1ALDH1A1MAPTHPGD
SCHEMBL6548638 0.90 HTT (0.32) HTTMEN1ALDH1A1MAPTHPGD
SCHEMBL6549664 0.90 THRB (0.33) THRBS1PR2S1PR1S1PR3LPAR2
SCHEMBL6549669 0.90 THRB (0.33) THRBS1PR2S1PR1S1PR3LPAR2
SCHEMBL6549963 0.90 THRB (0.33) THRBS1PR2S1PR1S1PR3LPAR2
SCHEMBL6549967 0.90 THRB (0.33) THRBS1PR2S1PR1S1PR3LPAR2
SCHEMBL6548480 0.90 HTT (0.30) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 THRB 1780/4885S1PR2 2362/4885S1PR1 2205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.