SCHEMBL6547895

SCHEMBL6547895

CCC(C)O/N=C/c1ccc(COc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GCGR P47871 4/20 0.34
KMT2A Q03164 7/20 0.33
MAPT P10636 7/20 0.33
LMNA P02545 5/20 0.33
MEN1 O00255 5/20 0.33
NPSR1 Q6W5P4 2/20 0.33
SMN1; SMN2 Q16637 5/20 0.33
NPC1 O15118 4/20 0.33
RAB9A P51151 4/20 0.33
CASP3 P42574 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
CCR5 P51681 1/20 0.32
KDM4E B2RXH2 1/20 0.32
CCR6 P51684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6547615 1.00 GCGR (0.34) GCGRKMT2AMAPTLMNAMEN1
SCHEMBL6549153 0.91 PPARG (0.36) GCGRKMT2AMAPTLMNAMEN1
SCHEMBL6549150 0.91 PPARG (0.36) GCGRKMT2AMAPTLMNAMEN1
SCHEMBL6547808 0.90 LMNA (0.31) LMNAPOLB
SCHEMBL6548476 0.90 LMNA (0.31) LMNAPOLB
SCHEMBL6549056 0.89 LMNA (0.33) KMT2AMAPTLMNAMEN1NPSR1
SCHEMBL6549363 0.89 PPARG (0.31) KMT2AMAPTLMNAMEN1POLB
SCHEMBL6549054 0.89 LMNA (0.33) KMT2AMAPTLMNAMEN1NPSR1
SCHEMBL6549358 0.89 PPARG (0.31) KMT2AMAPTLMNAMEN1POLB
SCHEMBL6549643 0.89 LMNA (0.30) LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP claimed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US claimed
EP-0975586-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION Sumitomo Chemical Company, Limited (JP) 2000-02-02 EP claimed
WO-1998045254-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-15 WO claimed
JP-11152258-A None JP disclosed
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed
JP-H11152258-A OXIME-BASED COMPOUND, ITS USE AND INTERMEDIATE FOR PRODUCING THE SAME COMPOUND SUMITOMO CHEM CO LTD 1999-06-08 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 GCGR 2537/4885KMT2A 2985/4885MAPT 4623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.