SCHEMBL6547995

SCHEMBL6547995

O=C(O)c1ccc(Br)cc1.[SnH2]

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.67
TP53 P04637 1/20 0.67
CES2 O00748 2/20 0.62
CES1 P23141 2/20 0.62
SRD5A2 P31213 1/20 0.57
RXRA P19793 1/20 0.57
RXRB P28702 1/20 0.57
CA1 P00915 4/20 0.56
CA2 P00918 4/20 0.56
CA12 O43570 1/20 0.55
CA3 P07451 1/20 0.55
TYR P14679 1/20 0.55
DRD1 P21728 1/20 0.55
CA4 P22748 1/20 0.55
CA6 P23280 1/20 0.55
CA5A P35218 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55
CA14 Q9ULX7 1/20 0.55
CA5B Q9Y2D0 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL71380 0.97 TSHR (0.71) TSHRTP53CES2CES1SRD5A2
SCHEMBL9317004 0.94 TSHR (0.67) TSHRTP53CES2CES1SRD5A2
SCHEMBL8767088 0.94 TSHR (0.67) TSHRTP53CES2CES1SRD5A2
SCHEMBL9318309 0.94 TSHR (0.67) TSHRTP53CES2CES1SRD5A2
SCHEMBL10614159 0.94 TSHR (0.67) TSHRTP53CES2CES1SRD5A2
SCHEMBL10604961 0.94 TSHR (0.67) TSHRTP53CES2CES1SRD5A2
Methane SCHEMBL16836109 0.94 TSHR (0.67) TSHRTP53CES2CES1SRD5A2
SCHEMBL8487555 0.94 TSHR (0.67) TSHRTP53CES2CES1SRD5A2
Hydrochloric Acid SCHEMBL532752 0.94 TSHR (0.67) TSHRTP53CES2CES1SRD5A2
Methyl Alcohol SCHEMBL38656404 0.92 TSHR (0.63) TSHRTP53CES2CES1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0757081-B1 Curable oil- and water-repellent silicone composition DOW CORNING TORAY SILICONE (JP) 2002-06-05 EP claimed
US-5880227-A Curable oil-and water-repellent silicone composition DOW CORNING TORAY SILICONE CO., LTD. (JP) 1999-03-09 US claimed
EP-0757081-A2 Curable oil- and water-repellent silicone composition Dow Corning Toray Silicone Company Ltd. (JP) 1997-02-05 EP claimed
US-5446115-A Surface-treatment composition DOW CORNING TORAY SILICON CO., LTD. (JP) 1995-08-29 US claimed
EP-0641843-A1 Surface-treatment composition Dow Corning Toray Silicone Company, Limited (JP) 1995-03-08 EP claimed
EP-4299683-B1 SILICONE COATING AGENT COMPOSITION AND ARTICLE SHINETSU CHEMICAL CO (JP) 2026-02-11 EP disclosed
US-12391847-B2 Silicone coating agent composition and article SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-08-19 US disclosed
US-20240150612-A1 SILICONE COATING AGENT COMPOSITION AND ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-05-09 US disclosed
EP-4299683-A1 SILICONE COATING AGENT COMPOSITION AND ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-03 EP disclosed
CN-116917427-A Silicone coating agent composition and article 信越化学工业株式会社 2023-10-20 CN disclosed
WO-2022181369-A1 SILICONE COATING AGENT COMPOSITION AND ARTICLE 信越化学工業株式会社 2022-09-01 WO disclosed
CN-113402911-A Silicone coating agent composition and article 信越化学工业株式会社 2021-09-17 CN disclosed
EP-0784084-A1 Oil- and water-repellent coating composition Dow Corning Toray Silicone Company Ltd. (JP) 1997-07-16 EP disclosed
EP-0757081-A2 Curable oil- and water-repellent silicone composition Dow Corning Toray Silicone Company Ltd. (JP) 1997-02-05 EP disclosed
EP-0744443-A2 Curable silicone composition Dow Corning Toray Silicone Company Ltd. (JP) 1996-11-27 EP disclosed
US-5446115-A Surface-treatment composition DOW CORNING TORAY SILICON CO., LTD. (JP) 1995-08-29 US disclosed
EP-0641843-A1 Surface-treatment composition Dow Corning Toray Silicone Company, Limited (JP) 1995-03-08 EP disclosed
US-5371155-A Fluorosilicone resin and curable fluorosilicone resin composition DOW CORNING TORAY SILICONE CO., LTD. (JP) 1994-12-06 US disclosed
EP-0574928-A2 Fluorosilicone resin and curable fluorosilicone resin composition Dow Corning Toray Silicone Company, Limited (JP) 1993-12-22 EP disclosed
US-4267297-A CONTAINING ALKOXYLATED SILOXANES, ALKOXYSILANES AND AMINOALKOXYSILANES TORAY SILICONE COMPANY, LTD. (JP) 1981-05-12 US disclosed