SCHEMBL8487555

SCHEMBL8487555

O=C(O)c1ccc(Br)cc1.[KH]

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.67
TP53 P04637 1/20 0.67
CES2 O00748 2/20 0.62
CES1 P23141 2/20 0.62
SRD5A2 P31213 1/20 0.57
RXRA P19793 1/20 0.57
RXRB P28702 1/20 0.57
CA1 P00915 4/20 0.56
CA2 P00918 4/20 0.56
CA12 O43570 1/20 0.55
CA3 P07451 1/20 0.55
TYR P14679 1/20 0.55
DRD1 P21728 1/20 0.55
CA4 P22748 1/20 0.55
CA6 P23280 1/20 0.55
CA5A P35218 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55
CA14 Q9ULX7 1/20 0.55
CA5B Q9Y2D0 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL71380 0.97 TSHR (0.71) TSHRTP53CES2CES1SRD5A2
SCHEMBL9317004 0.94 TSHR (0.67) TSHRTP53CES2CES1SRD5A2
SCHEMBL10604961 0.94 TSHR (0.67) TSHRTP53CES2CES1SRD5A2
SCHEMBL6547995 0.94 TSHR (0.67) TSHRTP53CES2CES1SRD5A2
Methane SCHEMBL16836109 0.94 TSHR (0.67) TSHRTP53CES2CES1SRD5A2
Hydrochloric Acid SCHEMBL532752 0.94 TSHR (0.67) TSHRTP53CES2CES1SRD5A2
SCHEMBL8767088 0.94 TSHR (0.67) TSHRTP53CES2CES1SRD5A2
SCHEMBL9318309 0.94 TSHR (0.67) TSHRTP53CES2CES1SRD5A2
SCHEMBL10614159 0.94 TSHR (0.67) TSHRTP53CES2CES1SRD5A2
Methyl Alcohol SCHEMBL38656404 0.92 TSHR (0.63) TSHRTP53CES2CES1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101070300-B Linonene anologs and its preparing method and use UNIV SHENYANG PHARMACEUTICAL 2011-06-01 CN disclosed
CN-101070300-A Linonene anologs and its preparing method and use UNIV SHENYANG PHARMACY (CN) 2007-11-14 CN disclosed
US-5919753-A Cross-linking agent NYCOMED IMAGING AS (NO) 1999-07-06 US disclosed
US-5693321-A Polymers containing diester units NYCOMED IMAGING AS (NO) 1997-12-02 US disclosed
US-5534250-A METHYLENE DIESTER GROUPS, BIODEGRADABLE NYCOMED IMAGING AS (NO) 1996-07-09 US disclosed
EP-0547126-B1 BIODEGRADABLE POLYMERS CONTAINING DIESTER UNITS NYCOMED IMAGING AS (NO) 1996-02-28 EP disclosed
EP-0577659-B1 CROSS-LINKING AGENT NYCOMED IMAGING AS (NO) 1996-01-17 EP disclosed
EP-0577659-A1 CROSS-LINKING AGENT. HOLMES MICHAEL JOHN (GB) 1994-01-12 EP disclosed
EP-0547126-A1 POLYMERS CONTAINING DIESTER UNITS. NYCOMED IMAGING AS (NO) 1993-06-23 EP disclosed
WO-1992017436-A1 CROSS-LINKING AGENT HOLMES, MICHAEL, JOHN (GB) 1992-10-15 WO disclosed
WO-1992004392-A1 POLYMERS CONTAINING DIESTER UNITS HOLMES, MICHAEL, JOHN (GB) 1992-03-19 WO disclosed