SCHEMBL71380

SCHEMBL71380

O=C(O)c1ccc(Br)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.71
TP53 P04637 1/20 0.71
CES2 O00748 2/20 0.65
CES1 P23141 2/20 0.65
SRD5A2 P31213 1/20 0.60
CA1 P00915 4/20 0.59
CA2 P00918 4/20 0.59
RXRA P19793 1/20 0.59
RXRB P28702 1/20 0.59
CA12 O43570 1/20 0.57
CA3 P07451 1/20 0.57
TYR P14679 1/20 0.57
DRD1 P21728 1/20 0.57
CA4 P22748 1/20 0.57
CA6 P23280 1/20 0.57
CA5A P35218 1/20 0.57
CA7 P43166 1/20 0.57
CA9 Q16790 1/20 0.57
CA14 Q9ULX7 1/20 0.57
CA5B Q9Y2D0 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6547995 0.97 TSHR (0.67) TSHRTP53CES2CES1SRD5A2
SCHEMBL8767088 0.97 TSHR (0.67) TSHRTP53CES2CES1SRD5A2
SCHEMBL9318309 0.97 TSHR (0.67) TSHRTP53CES2CES1SRD5A2
SCHEMBL10614159 0.97 TSHR (0.67) TSHRTP53CES2CES1SRD5A2
SCHEMBL8487555 0.97 TSHR (0.67) TSHRTP53CES2CES1SRD5A2
SCHEMBL10604961 0.97 TSHR (0.67) TSHRTP53CES2CES1SRD5A2
Methane SCHEMBL16836109 0.97 TSHR (0.67) TSHRTP53CES2CES1SRD5A2
Hydrochloric Acid SCHEMBL532752 0.97 TSHR (0.67) TSHRTP53CES2CES1SRD5A2
SCHEMBL9317004 0.97 TSHR (0.67) TSHRTP53CES2CES1SRD5A2
Methyl Alcohol SCHEMBL38656404 0.95 TSHR (0.63) TSHRTP53CES2CES1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6156 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116903866-B Polyvinyl alcohol modified multifunctional powder slump retaining agent and preparation method thereof JIANGSU ARIT NEW MATERIALS CO.,LTD. (CN) 2026-05-26 CN claimed
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
US-12497636-B2 Recombinant Saccharomyces cerevisiae cells for cannabinoid production NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-12-16 US claimed
US-20250270185-A1 METHOD FOR PREPARATION OF IPTACOPAN HYDROCHLORIDE HANGZHOU CHEMINSPIRE TECHNOLOGIES CO., LTD. (CN) 2025-08-28 US claimed
CN-120136947-A 4-Androstenedione derivative and preparation method and application thereof 华东师范大学 2025-06-13 CN claimed
CN-120137643-A Composite material, preparation method thereof, photoelectric device and display device 广东聚华新型显示研究院 2025-06-13 CN claimed
US-12325707-B2 Process for preparing enantiomerically enriched JAK inhibitors SUN PHARMACEUTICAL INDUSTRIES, INC. (US) 2025-06-10 US claimed
EP-4559009-A2 PARTICLES Life Technologies AS (NO) 2025-05-28 EP claimed
CN-120005095-A Platinum metal polymer high molecular material, preparation method and application thereof 榆林学院 2025-05-16 CN claimed
CN-119930651-A Thiazolopiperidine-containing derivative, and preparation method and application thereof 南开大学 2025-05-06 CN claimed
EP-0206543-A2 Polyaromatic compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-12-30 EP claimed
EP-0204472-A2 Cleaning compositions THE PROCTER & GAMBLE COMPANY (US) 1986-12-10 EP claimed
US-4576728-A AMINE OXIDE, BENZOIC ACID DERIVATIVE HIGH VISCOSITY THE PROCTER & GAMBLE COMPANY (US) 1986-03-18 US claimed
EP-0144166-A2 Cleaning compositions THE PROCTER & GAMBLE COMPANY (US) 1985-06-12 EP claimed
US-4279995-A DIFFERENTIATE CITROBACTER AND OTHER ENTEROBACTERIACEAE BY USE OF 2-DEOXY-D-RIBOSE MCDONNELL DOUGLAS CORPORATION (US) 1981-07-21 US claimed
US-4243740-A Light sensitive compositions of polymethyl isopropenyl ketone TOKYO OHKA KOGYO KABUSHIKI KAISHA (JP) 1981-01-06 US claimed
US-4155872-A AMINE SALTS OF CARBOXYLIC ACID, INCREASED TURBIDITY AND RESPONSE SPEED SHARP CORPORATION (JP) 1979-05-22 US claimed
US-4152160-A PHOTOTHERMOGRAPHY, SILVER BEHENATE FUJI PHOTO FILM CO., LTD. (JP) 1979-05-01 US claimed
US-4025466-A CATALYTIC MIXTURE OF FUSED HETEROCYCLIC COMPOUND CONTAINING AMIDINE GROUP AND SALT OF CARBOXYLIC ACID S.A. PRB (BE) 1977-05-24 US claimed
US-3990980-A Hybrid liquid toners PHILIP A. HUNT CHEMICAL CORPORATION (US) 1976-11-09 US claimed