SCHEMBL654800

SCHEMBL654800

[CH2]CCCc1ncco1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5534837 0.94 FAAH (0.31)
SCHEMBL5543063 0.92 FAAH (0.33)
SCHEMBL7027055 0.84 FAAH (0.38)
SCHEMBL7022926 0.84 FAAH (0.38)
SCHEMBL7029638 0.84 FAAH (0.38)
SCHEMBL29086344 0.81 CYP1B1 (0.32)
SCHEMBL1495178 0.78
SCHEMBL4595010 0.78
SCHEMBL11005395 0.78
SCHEMBL6410587 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230104311-A1 NOVEL 6-SUBSTITUTED 7-DEAZAPURINES AND CORRESPONDING NUCLEOSIDES AS MEDICAMENTS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-04-06 US disclosed
EP-4106763-A1 NOVEL 6-SUBSTITUTED 7-DEAZAPURINES AND CORRESPONDING NUCLEOSIDES AS MEDICAMENTS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2022-12-28 EP disclosed
CN-115515593-A Novel 6-substituted 7-deazapurines and corresponding nucleosides as medicaments 勒芬天主教大学 2022-12-23 CN disclosed
EP-2864312-B1 NOVEL ANTI-CANCER THIOPHENE COMPOUNDS UNIV LEUVEN KATH (BE) 2021-09-22 EP disclosed
US-20210276988-A1 4,6-DI- AND 2,4,6-TRISUBSTITUTED QUINAZOLINE DERIVATIVES USEFUL FOR TREATING VIRAL INFECTIONS GILEAD SCIENCES, INC. 2021-09-09 US disclosed
US-10882851-B2 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections GILEAD SCIENCES, INC. (US) 2021-01-05 US disclosed
US-20190152974-A1 SUBSTITUTED PTERIDINES USEFUL FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTIONS GILEAD SCIENCES, INC. 2019-05-23 US disclosed
US-10144736-B2 Substituted pteridines useful for the treatment and prevention of viral infections GILEAD SCIENCES, INC. (US) 2018-12-04 US disclosed
EP-2923734-B1 PURINE ANALOGUES AND THEIR USE AS IMMUNOSUPPRESSIVE AGENTS UNIV LEUVEN KATH (BE) 2018-01-10 EP disclosed
US-9822127-B2 GAK modulators as antivirals THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2017-11-21 US disclosed
EP-1479682-A1 Immunosuppressive effects of pteridine derivatives 4 AZA Bioscience nv (BE) 2004-11-24 EP disclosed
WO-2004048352-A2 2-CYANOPYRROLIDINES AND THEIR ANALOGUES AS DPP-IV INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-06-10 WO disclosed
EP-0980082-B1 Photo-electrochemical cell using an organic electrolyte FUJI PHOTO FILM CO LTD (JP) 2004-05-19 EP disclosed
US-20040077859-A1 Immunosuppressive effects of pteridine derivatives 4 AZA BIOSCIENCE NV (BE) 2004-04-22 US disclosed
US-20030236255-A1 Immunosuppressive effects of pteridine derivatives 4 AZA BIOSCIENCE NV (BE) 2003-12-25 US disclosed
WO-2002043680-A1 FIXATION OF CARBOHYDRATES TO FIBROUS MATERIALS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-06-06 WO disclosed
WO-2002043678-A2 ENZYMATIC FIXATION OF DERIVATISED CARBOHYDRATES TO FIBROUS MATERIALS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-06-06 WO disclosed
EP-0980082-A2 Organic electrolyte for a photo-electrochemical cell Fuji Photo Film Co., Ltd. (JP) 2000-02-16 EP disclosed
US-4463006-A ANTICANCER, ANTITUMOR AGENTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1984-07-31 US disclosed
US-4460590-A ANTITUMOR AGENTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1984-07-17 US disclosed