SCHEMBL6548022

SCHEMBL6548022

CCc1ccccc1C=CC(C)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.40
HTT P42858 1/20 0.37
CHAT P28329 1/20 0.36
PTGER3 P43115 2/20 0.35
PTGER2 P43116 2/20 0.35
TBXA2R P21731 1/20 0.35
PTGDR Q13258 1/20 0.35
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
TAAR1 Q96RJ0 2/20 0.33
PTGER4 P35408 1/20 0.33
LMNA P02545 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SLC6A3 Q01959 1/20 0.33
TACR1 P25103 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6548016 1.00 TRPA1 (0.40) TRPA1HTTCHATPTGER3PTGER2
SCHEMBL6546259 0.77 CHAT (0.47) CHATPTGER3PTGER2TBXA2RPTGDR
SCHEMBL3314625 0.77 CHAT (0.47) CHATPTGER3PTGER2TBXA2RPTGDR
SCHEMBL6548122 0.77 ALDH1A1 (0.42) TRPA1LMNAMEN1KMT2ACYP1A2
SCHEMBL6548129 0.77 ALDH1A1 (0.42) TRPA1LMNAMEN1KMT2ACYP1A2
SCHEMBL6546760 0.72 ALDH1A1 (0.41) TRPA1
SCHEMBL16105737 0.72 CHAT (0.62) TRPA1CHATPTGER3PTGER2PTGER4
SCHEMBL6472671 0.72 CHAT (0.62) TRPA1CHATPTGER3PTGER2PTGER4
SCHEMBL468924 0.72 CHAT (0.62) TRPA1CHATPTGER3PTGER2PTGER4
SCHEMBL9494233 0.71 CHAT (0.40) CHATPTGER3PTGER2TBXA2RPTGDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed