Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97780 | 0.88 | TSHR (0.56) | TSHRCYP1A2LMNAKMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL1844352 | 0.85 | TSHR (0.53) | TSHRCYP1A2LMNAKMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL180144 | 0.85 | TSHR (0.53) | TSHRCYP1A2LMNAKMT2AHSD17B10 | |
| SCHEMBL16358111 | 0.80 | — | — | |
| SCHEMBL163253 | 0.80 | TSHR (0.72) | TSHRCYP1A2LMNAKMT2AHSD17B10 | |
| SCHEMBL5067235 | 0.80 | TSHR (0.48) | TSHRCYP1A2LMNAKMT2AHSD17B10 | |
| SCHEMBL14235175 | 0.78 | TSHR (0.46) | TSHRCYP1A2LMNAKMT2AHSD17B10 | |
| SCHEMBL14042508 | 0.78 | — | — | |
| SCHEMBL4407718 | 0.78 | TRPA1 (0.52) | TSHRALOX15ALDH1A1CYP3A4HPGD | |
| SCHEMBL19308751 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1191057-B1 | Silica reinforced rubber composition prepared with pretreated silica and article of manufacture | GOODYEAR TIRE & RUBBER (US) | 2004-12-01 | — | — | EP | claimed |
| US-6713549-B1 | UTILIZING NONALKOXYSILANE CONTAINING COUPLING AGENT; REDUCED ALCOHOL BYPRODUCT EVOLUTION | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-03-30 | — | — | US | claimed |
| EP-1191057-A1 | Silica reinforced rubber composition prepared with pretreated silica and article of manufacture | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2002-03-27 | — | — | EP | claimed |
| EP-1191057-B1 | Silica reinforced rubber composition prepared with pretreated silica and article of manufacture | GOODYEAR TIRE & RUBBER (US) | 2004-12-01 | — | — | EP | disclosed |
| US-6713549-B1 | UTILIZING NONALKOXYSILANE CONTAINING COUPLING AGENT; REDUCED ALCOHOL BYPRODUCT EVOLUTION | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-03-30 | — | — | US | disclosed |
| EP-1191057-A1 | Silica reinforced rubber composition prepared with pretreated silica and article of manufacture | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2002-03-27 | — | — | EP | disclosed |
| EP-0781801-B1 | Silica-filled rubber compositions containing dialkyleneamide polysulfides | GOODYEAR TIRE & RUBBER (US) | 1999-09-15 | — | — | EP | disclosed |
| EP-0781801-A1 | Silica-filled rubber compositions containing dialkyleneamide polysulfides | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-07-02 | — | — | EP | disclosed |
| US-5641820-A | SULFUR VULCANIZABLE ELASTOMERS WITH COUPLING AGENTS, FOR TIRE TREADS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-06-24 | — | — | US | disclosed |
| US-4322214-A | USING A SULFUR OR SULFURIZED VAT DYE IN AN ALKALINE BATH CONTAINING A MERCAPTO COMPOUND AND A SULFITE SALT; LEVELING | ASAHI CHEMICAL COMPANY LIMITED (JP) | 1982-03-30 | — | — | US | disclosed |