Sugi Predict

Sugi Predict / Compounds / SCHEMBL6548516

SCHEMBL6548516

SCHEMBL6548516

CC(=NOCCCCCOc1c(C)cc(OCC=C(Cl)Cl)cc1Cl)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PPARA Q07869 12/20 0.46
▸ PPARG P37231 11/20 0.46
▸ CYP3A4 P08684 3/20 0.39
▸ CYP1A2 P05177 2/20 0.39
▸ CYP2D6 P10635 2/20 0.39
▸ CYP2C9 P11712 2/20 0.39
▸ CYP2C19 P33261 2/20 0.39
▸ HIF1A Q16665 2/20 0.39
▸ MEN1 O00255 2/20 0.39
▸ LMNA P02545 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ KCNH2 Q12809 2/20 0.39
▸ SCN5A Q14524 2/20 0.39
▸ NFKB1 P19838 1/20 0.39
▸ SLC6A2 P23975 1/20 0.39
▸ SLC6A4 P31645 1/20 0.39
▸ ADRA1A P35348 1/20 0.39
▸ OPRK1 P41145 1/20 0.39
▸ SLC6A3 Q01959 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6547187 0.99 PPARA (0.47) PPARAPPARGCYP3A4CYP1A2CYP2D6
SCHEMBL6549771 0.97 PPARA (0.45) PPARAPPARGCYP3A4CYP1A2CYP2D6
SCHEMBL6548927 0.94 PPARA (0.45) PPARAPPARGCYP3A4CYP1A2CYP2D6
SCHEMBL6549355 0.94 PPARA (0.45) PPARAPPARGCYP3A4CYP1A2CYP2D6
SCHEMBL6549701 0.94 PPARA (0.46) PPARAPPARGCYP3A4CYP1A2CYP2D6
SCHEMBL6548449 0.92 PPARG (0.43) PPARAPPARGCYP3A4CYP1A2CYP2D6
SCHEMBL6549641 0.90 SLC6A4 (0.38) PPARAPPARGSLC6A4
SCHEMBL6549134 0.90 PPARA (0.47) PPARAPPARGCYP3A4CYP1A2CYP2D6
SCHEMBL6547280 0.89 SLC6A4 (0.38) PPARAPPARGSLC6A4
SCHEMBL6549827 0.89 PPARG (0.40) PPARAPPARGCYP3A4CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 — — EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 — — US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 — — US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 — — US disclosed
EP-0975586-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION Sumitomo Chemical Company, Limited (JP) 2000-02-02 — — EP disclosed
WO-1998045254-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 PPARA 2987/4885PPARG 2821/4885CYP3A4 382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.