SCHEMBL6547280

SCHEMBL6547280

CC(=NOCCCCOc1c(C)cc(OCC=C(Cl)Cl)cc1Cl)c1ccc(Cl)cc1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 2/20 0.38
PPARA Q07869 13/20 0.38
PPARG P37231 12/20 0.38
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
PSEN1 P49768 2/20 0.34
PSEN2 P49810 2/20 0.34
APH1B Q8WW43 2/20 0.34
NCSTN Q92542 2/20 0.34
APH1A Q96BI3 2/20 0.34
PSENEN Q9NZ42 2/20 0.34
KDM4E B2RXH2 1/20 0.34
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6549641 0.99 SLC6A4 (0.38) SLC6A4PPARAPPARGNPC1RAB9A
SCHEMBL6549805 0.98 SLC6A4 (0.36) SLC6A4PPARAPPARGNPC1RAB9A
SCHEMBL6549954 0.94 NPC1 (0.39) SLC6A4PPARAPPARGNPC1RAB9A
SCHEMBL6548572 0.93 NPC1 (0.39) SLC6A4PPARAPPARGNPC1RAB9A
SCHEMBL6548630 0.92 PPARA (0.46) PPARAPPARGNPC1RAB9AKDM4E
SCHEMBL6549849 0.92 NPC1 (0.37) SLC6A4PPARAPPARGNPC1RAB9A
SCHEMBL6548877 0.91 PPARA (0.45) PPARAPPARGNPC1RAB9AKDM4E
SCHEMBL6549804 0.90 PPARA (0.43) PPARAPPARGNPC1RAB9AHTT
SCHEMBL6547187 0.90 PPARA (0.47) SLC6A4PPARAPPARG
SCHEMBL6547702 0.89 NPC1 (0.39) SLC6A4PPARAPPARGNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 SLC6A4 4778/4885PPARA 2987/4885PPARG 2821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.