SCHEMBL6548591

SCHEMBL6548591

CON=C(c1ccc(COc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)cc1)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GCGR P47871 4/20 0.36
ADCYAP1R1 P41586 4/20 0.35
MAPT P10636 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CCR5 P51681 1/20 0.31
LMNA P02545 2/20 0.31
HTT P42858 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31
MAOB P27338 1/20 0.30
MRGPRX4 Q96LA9 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6547777 0.91 GCGR (0.33) GCGRADCYAP1R1MAPTMEN1KMT2A
SCHEMBL6548541 0.91 GCGR (0.32) GCGRADCYAP1R1MAPTMEN1KMT2A
SCHEMBL6549679 0.90 GCGR (0.32) GCGRADCYAP1R1MAPTMEN1KMT2A
SCHEMBL6547036 0.90 F2 (0.33)
SCHEMBL6547828 0.89 CYP3A4 (0.30) CYP3A4
SCHEMBL6548515 0.89 GCGR (0.32) GCGRADCYAP1R1MAPTMEN1KMT2A
SCHEMBL6548169 0.88 GCGR (0.31) GCGRADCYAP1R1
SCHEMBL6547769 0.87 ALDH1A1 (0.31) GCGRMAPT
SCHEMBL6549650 0.87 ESR1 (0.34) GCGR
SCHEMBL6548842 0.85 HRH3 (0.43) GCGRADCYAP1R1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed
EP-0975586-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION Sumitomo Chemical Company, Limited (JP) 2000-02-02 EP disclosed
WO-1998045254-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 GCGR 2537/4885ADCYAP1R1 3455/4885MAPT 4623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.