Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6547399 | 0.84 | CYP4F2 (0.51) | CA12CA1METCA4CA6 | |
| SCHEMBL11378276 | 0.78 | ALDH1A1 (0.47) | CA12CA1METCA4CA6 | |
| SCHEMBL6548882 | 0.76 | CA12 (0.38) | CA12CA1METCA4CA6 | |
| SCHEMBL6548879 | 0.76 | CA12 (0.38) | CA12CA1METCA4CA6 | |
| SCHEMBL16015107 | 0.75 | HDAC3 (0.41) | CA12CA1METCA4CA6 | |
| SCHEMBL12824956 | 0.72 | TYR (0.68) | CA12CA1CA4CA6CA5A | |
| SCHEMBL6549672 | 0.71 | CA1 (0.44) | CA12CA1CA4CA6CA5A | |
| SCHEMBL13176452 | 0.71 | MAPT (0.62) | MAPTMAOBMMP1MMP2MMP9 | |
| SCHEMBL932809 | 0.70 | MAPT (0.67) | MAPTCYP1A2HDAC8HDAC2MAOB | |
| SCHEMBL30393958 | 0.70 | MAPT (0.67) | MAPTCYP1A2HDAC8HDAC2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100778-B1 | OXIDISED SULFURATED DISTAMYCIN DERIVATIVES, PROCESS FOR PREPARING THEM, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA ITALIA SPA (IT) | 2004-12-01 | — | — | EP | disclosed |
| EP-1100777-B1 | SULFURATED DISTAMYCIN DERIVATIVES, PROCESS FOR PREPARING THEM, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA ITALIA SPA (IT) | 2003-05-28 | — | — | EP | disclosed |