SCHEMBL932809

SCHEMBL932809

O=C(S)/C=C/c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.67
HDAC3 O15379 2/20 0.67
HDAC4 P56524 2/20 0.67
HDAC1 Q13547 2/20 0.67
HDAC2 Q92769 2/20 0.67
HDAC8 Q9BY41 2/20 0.67
HDAC6 Q9UBN7 2/20 0.67
PLIN1 O60240 2/20 0.67
LMNA P02545 2/20 0.67
RECQL P46063 2/20 0.67
PLIN5 Q00G26 2/20 0.67
ABHD5 Q8WTS1 2/20 0.67
ALDH1A1 P00352 2/20 0.67
F3 P13726 2/20 0.67
TNKS O95271 1/20 0.67
HCAR2 Q8TDS4 1/20 0.67
HDAC7 Q8WUI4 1/20 0.67
HDAC10 Q969S8 1/20 0.67
HDAC11 Q96DB2 1/20 0.67
TNKS2 Q9H2K2 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30393958 1.00 MAPT (0.67) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL11832231 0.87 HDAC2 (0.65) MAPTHDAC3HDAC4HDAC1HDAC2
Cinnamic Acid SCHEMBL50466 0.80 HCAR2 (1.00) MAPTHDAC3HDAC4HDAC1HDAC2
Cinnamic Acid SCHEMBL653828 0.80 HCAR2 (1.00) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL20846 0.80 MAPT (1.00) MAPTHDAC3HDAC4HDAC1HDAC2
Cinnamic Acid SCHEMBL1332 0.80 HCAR2 (1.00) MAPTHDAC3HDAC4HDAC1HDAC2
Cinnamic Acid SCHEMBL1706935 0.80 HCAR2 (1.00) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL20518814 0.80 MAPT (1.00) MAPTHDAC3HDAC4HDAC1HDAC2
SCHEMBL20856054 0.80 MAPT (1.00) MAPTHDAC3HDAC4HDAC1HDAC2
Cinnamic Acid SCHEMBL653827 0.80 HCAR2 (1.00) MAPTHDAC3HDAC4HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108367167-A Using comprising it is modified can photodimerization polymer compositions-treated keratin substances method 莱雅公司 2018-08-03 CN claimed
US-20260117056-A1 PVC COMPOUND Value Wholesaler D/B/A Value Windows and Doors, INC. (US) 2026-04-30 US disclosed
US-20250360238-A1 SUPERCRITICAL CARBON DIOXIDE STERILIZATION OF BIOLOGICAL TISSUE InnovMedics, LLC (US) 2025-11-27 US disclosed
US-20240336740-A1 POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF HENKEL AG & CO KGAA (DE) 2024-10-10 US disclosed
US-20240336575-A1 POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF HENKEL AG & CO KGAA (DE) 2024-10-10 US disclosed
US-20240327341-A1 POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF HENKEL AG & CO KGAA (DE) 2024-10-03 US disclosed
CN-118401566-A Polythiol compound and process for producing the same 汉高股份有限及两合公司 2024-07-26 CN disclosed
CN-118401498-A Polythiol compound and process for producing the same 汉高股份有限及两合公司 2024-07-26 CN disclosed
EP-4198028-B1 POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF HENKEL AG & CO KGAA (DE) 2024-07-17 EP disclosed
EP-4198062-B1 POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF HENKEL AG & CO KGAA (DE) 2024-07-17 EP disclosed
WO-1990004625-A2 AMIDE CONTAINING FRICTION MODIFIER FOR USE IN POWER TRANSMISSION FLUIDS EXXON CHEMICAL COMPANY (US) 1990-05-03 WO disclosed
EP-0357217-A2 Ethylene alpha-olefin copolymer substituted amino phenol mannich base lubricant dispersant additives EXXON CHEMICAL PATENTS INC. (US) 1990-03-07 EP disclosed
EP-0356010-A1 Ethylene alpha-olefin polymer substituted Mannich base lubricant dispersant additives EXXON CHEMICAL PATENTS INC. (US) 1990-02-28 EP disclosed
EP-0353935-A1 Ethylene alpha-olefin polymer substituted mono-and dicarboxylic acid lubricant dispersant additives EXXON CHEMICAL PATENTS INC. (US) 1990-02-07 EP disclosed
EP-0336664-A2 Improved dispersant additives derived from amido-amine adducts EXXON CHEMICAL PATENTS INC. (US) 1989-10-11 EP disclosed
US-4857217-A ADDUCT OF POLYOLEFIN MODIFIED WITH AN ACID AND POLYAMINE MODIFIED WITH (THIO)AMIDO COMPOUND EXXON CHEMICAL PATENTS INC. (US) 1989-08-15 US disclosed
EP-0319229-A2 Improved dispersant additives derived from amido-amines EXXON CHEMICAL PATENTS INC. (US) 1989-06-07 EP disclosed
US-4128510-A 2,5-DIMERCAPTO-1,3,4-THIADIAZOLES HERCULES INCORPORATED (US) 1978-12-05 US disclosed
US-3996287-A SULFURIZATION OF A 2-ENE-1,4-DIONE; HYDROLYZING INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-12-07 US disclosed
US-3931270-A Process for producing 2-thia substituted 1,4 diones INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260117056-A1 PVC COMPOUND ORAI1, TRPV3, CACNA2D3 MAPT 2124/4885HDAC3 1227/4885HDAC4 2036/4885
US-20240336575-A1 POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF VRK2, VRK1, PTMS MAPT 4083/4885HDAC3 3872/4885HDAC4 4608/4885
US-20240327341-A1 POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF VCL, C9, VRK1 MAPT 3991/4885HDAC3 930/4885HDAC4 2744/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.