SCHEMBL6548965

SCHEMBL6548965

CC1(C)C(=O)[N]C(=O)N1Cc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.47
ELANE P08246 5/20 0.47
ALDH1A1 P00352 3/20 0.45
CTSG P08311 2/20 0.41
PRTN3 P24158 1/20 0.41
F2 P00734 1/20 0.41
PLG P00747 1/20 0.41
CMA1 P23946 1/20 0.41
CTRC Q99895 1/20 0.41
AMPD2 Q01433 2/20 0.40
NPSR1 Q6W5P4 1/20 0.39
GSK3A P49840 1/20 0.39
GSK3B P49841 1/20 0.39
MGLL Q99685 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
THRB P10828 1/20 0.38
CA12 O43570 1/20 0.38
CA9 Q16790 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10597765 0.76 MMP2 (0.44) GAAELANEALDH1A1MEN1KMT2A
SCHEMBL7449986 0.71 ELANE (0.50) GAAELANEALDH1A1CTSGPRTN3
SCHEMBL13985003 0.69 GAA (0.47) GAAELANEALDH1A1CTSGPRTN3
SCHEMBL2246388 0.69 GAA (0.51) GAAELANEALDH1A1CTSGPRTN3
SCHEMBL19923520 0.69 ELANE (0.61) ELANEALDH1A1CTSGPRTN3F2
SCHEMBL19923521 0.69 ELANE (0.47) GAAELANEALDH1A1CTSGPRTN3
SCHEMBL2027394 0.68 ALDH1A1 (0.72) ELANEALDH1A1
SCHEMBL9357173 0.68 ELANE (0.50) GAAELANEALDH1A1CTSGPRTN3
SCHEMBL19923557 0.67 ELANE (0.45) GAAELANEALDH1A1CTSGPRTN3
SCHEMBL19923601 0.67 ELANE (0.45) GAAELANEALDH1A1CTSGPRTN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0877288-B1 Silver halide light-sensitive color photographic material KONISHIROKU PHOTO IND (JP) 2004-12-01 EP disclosed
US-5998123-A MERCAPTOPYRAZOLONE DERIVATIVE COUPLERS KONICA CORPORATION (JP) 1999-12-07 US disclosed
EP-0877288-A1 Silver halide light-sensitive color photographic material KONICA CORPORATION (JP) 1998-11-11 EP disclosed
EP-0304067-B1 Silver halide color photographic light-sensitive material containing epoxy compound FUJI PHOTO FILM CO LTD (JP) 1993-11-10 EP disclosed
US-5183731-A Storage stability yellow images; heat and water resistant, colorfastness FUJI PHOTO FILM CO., LTD. (JP) 1993-02-02 US disclosed
US-5055386-A Excellent image storing properties FUJI PHOTO FILM CO., LTD. (JP) 1991-10-08 US disclosed
US-4929540-A 5-PYRAZOLONE COUPLER WITH NITROGEN-HETEROCYCLE-THIOELIMINATABLE GROUP FUJI PHOTO FILM CO., LTD. (JP) 1990-05-29 US disclosed
EP-0304067-A2 Silver halide color photographic light-sensitive material containing epoxy compound Fuji Photo Film Co., Ltd. (JP) 1989-02-22 EP disclosed