SCHEMBL6549030

SCHEMBL6549030

CON=Cc1ccc(CCCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)cc1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPT P10636 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
PPARG P37231 2/20 0.32
PPARA Q07869 2/20 0.32
CYP3A4 P08684 2/20 0.32
HTT P42858 1/20 0.32
ALDH1A1 P00352 2/20 0.31
GAA P10253 2/20 0.31
REN P00797 2/20 0.30
MAPK1 P28482 1/20 0.30
MET P08581 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6549027 1.00 SRC (0.33) SRCL3MBTL1MEN1KMT2AMAPT
SCHEMBL6548569 0.97 SRC (0.33) SRCL3MBTL1MEN1KMT2AMAPT
SCHEMBL6548565 0.97 SRC (0.33) SRCL3MBTL1MEN1KMT2AMAPT
SCHEMBL6548188 0.95 SRC (0.34) SRCL3MBTL1MEN1KMT2AMAPT
SCHEMBL6548192 0.95 SRC (0.34) SRCL3MBTL1MEN1KMT2AMAPT
SCHEMBL6549217 0.90 L3MBTL1 (0.38) L3MBTL1MEN1KMT2AMAPTTDP1
SCHEMBL6549222 0.90 L3MBTL1 (0.38) L3MBTL1MEN1KMT2AMAPTTDP1
SCHEMBL6550056 0.90 MEN1 (0.36) L3MBTL1MEN1KMT2AMAPTTDP1
SCHEMBL6550058 0.90 MEN1 (0.36) L3MBTL1MEN1KMT2AMAPTTDP1
SCHEMBL6549585 0.89 L3MBTL1 (0.38) SRCL3MBTL1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed
EP-0975586-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION Sumitomo Chemical Company, Limited (JP) 2000-02-02 EP disclosed
WO-1998045254-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 SRC 1678/4885L3MBTL1 876/4885MEN1 4425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.