SCHEMBL6549111

SCHEMBL6549111

ClC(Cl)=CCOc1cc(Cl)c(OCCc2ccc(C=NOCCCc3ccccc3)cc2)c(Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PPARG P37231 6/20 0.46
PPARA Q07869 5/20 0.46
ACHE P22303 1/20 0.38
TAAR1 Q96RJ0 1/20 0.36
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
MAPT P10636 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
HPGD P15428 3/20 0.34
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
PTGES O14684 1/20 0.32
ALOX5 P09917 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6549105 1.00 PPARG (0.46) PPARGPPARAACHETAAR1MEN1
SCHEMBL6549999 0.91 MEN1 (0.41) PPARGPPARAACHETAAR1MEN1
SCHEMBL6550005 0.91 MEN1 (0.41) PPARGPPARAACHETAAR1MEN1
SCHEMBL6549222 0.90 L3MBTL1 (0.38) PPARGPPARAACHEMEN1KMT2A
SCHEMBL6549217 0.90 L3MBTL1 (0.38) PPARGPPARAACHEMEN1KMT2A
SCHEMBL6547759 0.89 L3MBTL1 (0.36) PPARGPPARAMEN1KMT2AL3MBTL1
SCHEMBL6547756 0.89 L3MBTL1 (0.36) PPARGPPARAMEN1KMT2AL3MBTL1
SCHEMBL6547276 0.88 UNG (0.39) PPARGPPARAACHETAAR1MEN1
SCHEMBL6548576 0.88 UNG (0.37) PPARGPPARAACHETAAR1MEN1
SCHEMBL6547281 0.88 UNG (0.39) PPARGPPARAACHETAAR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed
EP-0975586-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION Sumitomo Chemical Company, Limited (JP) 2000-02-02 EP disclosed
WO-1998045254-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 PPARG 2821/4885PPARA 2987/4885ACHE 228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.