SCHEMBL654923

SCHEMBL654923

[C]1C=CN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6559802 0.35
SCHEMBL29889134 0.35
Water SCHEMBL25437472 0.35
SCHEMBL5134016 0.35
SCHEMBL29612863 0.35
Hydrochloric Acid SCHEMBL72335 0.25
Fluoride Ion SCHEMBL73611 0.25
SCHEMBL74539 0.25
SCHEMBL1629906 0.25
SCHEMBL1179177 0.25

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210163495-A1 TRICYCLIC COMPOUNDS AS CYP1 INHIBITORS THE GENERAL HOSPITAL CORPORATION 2021-06-03 US claimed
EP-3641756-A1 TRICYCLIC COMPOUNDS AS CYP1 INHIBITORS The General Hospital Corporation (US) 2020-04-29 EP claimed
US-10206398-B2 Five-membered C-N-attached aryl sulphide and aryl sulphoxide derivatives as pesticides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-02-19 US claimed
WO-2018232251-A1 TRICYCLIC COMPOUNDS AS CYP1 INHIBITORS THE GENERAL HOSPITAL CORPORATION (US) 2018-12-20 WO claimed
EP-3230267-B1 FIVE-MEMBERED C-N LINKED ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2018-09-26 EP claimed
US-20170367333-A1 FIVE-MEMBERED C-N-ATTACHED ARYL SULPHIDE AND ARYL SULPHOXIDE DERIVATIVES AS PESTICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-12-28 US claimed
EP-3230267-A1 FIVE-MEMBERED C-N BONDED ARYL SULPHIDE AND ARYL SULPHOXIDE DERIVATIVES AS PEST CONTROL AGENTS Bayer CropScience Aktiengesellschaft (DE) 2017-10-18 EP claimed
WO-2016091857-A1 FIVE-MEMBERED C-N BONDED ARYL SULPHIDE AND ARYL SULPHOXIDE DERIVATIVES AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-06-16 WO claimed
EP-1658081-A2 IMMUNOSUPPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES 4 AZA Bioscience nv (BE) 2006-05-24 EP claimed
WO-2005021003-A2 IMMUNOSUPPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES 4 AZA BIOSCIENCE NV (BE) 2005-03-10 WO claimed
US-20040186156-A1 Substituted N-(1,4,5,6,-tetrahydro-cyclopentapyrazol-3-yl) derivatives, their production and use as pharmaceutical agents BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2004-09-23 US claimed
US-6747046-B2 ANTITUMOR, ANTI CELL PROLIFERATION SCHERING AKTIENGESELLSCHAFT (DE) 2004-06-08 US claimed
US-20040077859-A1 Immunosuppressive effects of pteridine derivatives 4 AZA BIOSCIENCE NV (BE) 2004-04-22 US claimed
US-20030236255-A1 Immunosuppressive effects of pteridine derivatives 4 AZA BIOSCIENCE NV (BE) 2003-12-25 US claimed
US-20030212121-A1 Substituted N-(1,4,5,6-tetrahydro-cyclopentapyrazol-3-yl) derivatives, their production and use as pharmaceutical agents BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2003-11-13 US claimed
WO-2003029223-A1 SUBSTITUTED N-(1,4,5,6-TETRAHYDROCYCLOPENTAPYRAZOL-3-YL) DERIVATIVES AND THE USE OF THE SAME FOR THE TREATMENT OF CANCER SCHERING AKTIENGESELLSCHAFT (DE) 2003-04-10 WO claimed
US-20240231224-A9 HALOGEN-AND ALIPHATIC-CONTAINING ORGANOTIN PHOTORESISTS AND METHODS THEREOF LAM RESEARCH CORPORATION 2024-07-11 US disclosed
US-12030858-B2 PARP inhibitors for treating cancer and asthma OREGON HEALTH & SCIENCE UNIVERSITY (US) 2024-07-09 US disclosed
US-20030212121-A1 Substituted N-(1,4,5,6-tetrahydro-cyclopentapyrazol-3-yl) derivatives, their production and use as pharmaceutical agents BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2003-11-13 US disclosed
WO-2003029223-A1 SUBSTITUTED N-(1,4,5,6-TETRAHYDROCYCLOPENTAPYRAZOL-3-YL) DERIVATIVES AND THE USE OF THE SAME FOR THE TREATMENT OF CANCER SCHERING AKTIENGESELLSCHAFT (DE) 2003-04-10 WO disclosed