SCHEMBL6549508

SCHEMBL6549508

CCON=Cc1ccc(COc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.38
MAPT P10636 6/20 0.38
MEN1 O00255 6/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
TDP1 Q9NUW8 1/20 0.38
LMNA P02545 6/20 0.37
NPSR1 Q6W5P4 2/20 0.37
NPC1 O15118 5/20 0.35
RAB9A P51151 5/20 0.35
SMN1; SMN2 Q16637 5/20 0.35
CASP3 P42574 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP6 Q9GZR1 1/20 0.35
KDM4E B2RXH2 3/20 0.34
CCR6 P51684 1/20 0.34
UBE2N P61088 1/20 0.34
CCR5 P51681 1/20 0.34
GAA P10253 2/20 0.34
MITF O75030 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6549505 1.00 KMT2A (0.38) KMT2AMAPTMEN1L3MBTL1TDP1
SCHEMBL6548054 0.92 KMT2A (0.40) KMT2AMAPTMEN1L3MBTL1TDP1
SCHEMBL6548050 0.92 KMT2A (0.40) KMT2AMAPTMEN1L3MBTL1TDP1
SCHEMBL6548649 0.90 KMT2A (0.37) KMT2AMAPTMEN1L3MBTL1TDP1
SCHEMBL6548646 0.90 KMT2A (0.37) KMT2AMAPTMEN1L3MBTL1TDP1
SCHEMBL6549234 0.90 KMT2A (0.42) KMT2AMAPTMEN1L3MBTL1TDP1
SCHEMBL6549238 0.90 KMT2A (0.42) KMT2AMAPTMEN1L3MBTL1TDP1
SCHEMBL6548340 0.89 MEN1 (0.34) KMT2AMAPTMEN1L3MBTL1TDP1
SCHEMBL6548336 0.89 MEN1 (0.34) KMT2AMAPTMEN1L3MBTL1TDP1
SCHEMBL6549966 0.89 KMT2A (0.37) KMT2AMAPTMEN1L3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed
EP-0975586-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION Sumitomo Chemical Company, Limited (JP) 2000-02-02 EP disclosed
WO-1998045254-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 KMT2A 2985/4885MAPT 4623/4885MEN1 4425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.