SCHEMBL6548340

SCHEMBL6548340

CCON=Cc1ccc(CCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)cc1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
MAPT P10636 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
ALDH1A1 P00352 4/20 0.33
HTT P42858 3/20 0.33
HPGD P15428 2/20 0.33
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PPARG P37231 3/20 0.31
PPARA Q07869 3/20 0.31
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
PKM P14618 1/20 0.30
CYP2C19 P33261 1/20 0.30
NMT1 P30419 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6548336 1.00 MEN1 (0.34) MEN1KMT2AMAPTL3MBTL1TDP1
SCHEMBL6550058 0.95 MEN1 (0.36) MEN1KMT2AMAPTL3MBTL1TDP1
SCHEMBL6550056 0.95 MEN1 (0.36) MEN1KMT2AMAPTL3MBTL1TDP1
SCHEMBL6548190 0.94 MEN1 (0.35) MEN1KMT2AMAPTL3MBTL1TDP1
SCHEMBL6548187 0.94 MEN1 (0.35) MEN1KMT2AMAPTL3MBTL1TDP1
SCHEMBL6547756 0.93 L3MBTL1 (0.36) MEN1KMT2AMAPTL3MBTL1TDP1
SCHEMBL6547759 0.93 L3MBTL1 (0.36) MEN1KMT2AMAPTL3MBTL1TDP1
SCHEMBL6549863 0.91 L3MBTL1 (0.34) MEN1KMT2AMAPTL3MBTL1TDP1
SCHEMBL6549505 0.89 KMT2A (0.38) MEN1KMT2AMAPTL3MBTL1TDP1
SCHEMBL6549508 0.89 KMT2A (0.38) MEN1KMT2AMAPTL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed
EP-0975586-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION Sumitomo Chemical Company, Limited (JP) 2000-02-02 EP disclosed
WO-1998045254-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 MEN1 4425/4885KMT2A 2985/4885MAPT 4623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.