SCHEMBL6549512

SCHEMBL6549512

CCCCC(=O)C[S+](C)C(C)(C)C.CCCCS(=O)(=O)[O-]

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.34
CES2 O00748 1/20 0.34
EPHX2 P34913 1/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
GRK2 P25098 1/20 0.33
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CA1 P00915 1/20 0.32
BBOX1 O75936 2/20 0.31
HAO1 Q9UJM8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6548750 0.95 CES1 (0.36) CES1CES2EPHX2MEN1LMNA
SCHEMBL6550576 0.94 HAO1 (0.38) CES1CES2EPHX2MEN1LMNA
SCHEMBL6550895 0.94 EPHX2 (0.33) CES1CES2EPHX2MEN1LMNA
SCHEMBL6551035 0.89 EPHX2 (0.34) EPHX2MEN1LMNAPOLBGRK2
SCHEMBL6726179 0.85 CES1 (0.41) CES1CES2MEN1KMT2ACA1
Trifluoromethanesulfonic Acid SCHEMBL6549345 0.85 CES1 (0.34) CES1CES2MEN1KMT2ACA1
SCHEMBL6549744 0.84 EPHX2 (0.35) EPHX2MEN1LMNAPOLBGRK2
SCHEMBL6549443 0.84 CES1 (0.39) CES1CES2EPHX2MEN1LMNA
SCHEMBL6549652 0.83 EPHX2 (0.34) CES1CES2EPHX2MEN1LMNA
SCHEMBL6550467 0.81 EPHX2 (0.33) EPHX2MEN1LMNAPOLBGRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1167349-B1 Chemical amplifying type positive resist composition SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6548220-B2 Containing acid generator SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-04-15 US disclosed
US-20020015913-A1 Chemical amplifying type positive resist composition and sulfonium salt SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-02-07 US disclosed
EP-1167349-A1 Chemical amplifying type positive resist composition and sulfonium salt SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-02 EP disclosed