Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 11/20 | 0.55 |
| ▸ | CXCR1 | P25024 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6549708 | 0.89 | MEN1 (0.68) | CXCR2CXCR1MEN1KMT2ALMNA | |
| SCHEMBL6550093 | 0.83 | MEN1 (0.57) | CXCR2MEN1KMT2ALMNAMAPT | |
| SCHEMBL6550860 | 0.79 | MEN1 (0.56) | CXCR2CXCR1MEN1KMT2ALMNA | |
| SCHEMBL7490549 | 0.77 | CXCR2 (0.67) | CXCR2CXCR1MEN1KMT2ALMNA | |
| SCHEMBL7211784 | 0.75 | CXCR2 (0.51) | CXCR2CXCR1MEN1KMT2ALMNA | |
| SCHEMBL7487864 | 0.73 | CXCR2 (0.61) | CXCR2CXCR1MEN1KMT2ALMNA | |
| SCHEMBL10530781 | 0.73 | MEN1 (1.00) | MEN1KMT2ALMNAMAPTGAA | |
| SCHEMBL31061375 | 0.72 | CXCR2 (1.00) | CXCR2CXCR1MEN1KMT2ALMNA | |
| SCHEMBL7491596 | 0.72 | CXCR2 (1.00) | CXCR2CXCR1MEN1KMT2ALMNA | |
| SCHEMBL1880282 | 0.72 | CXCR2 (0.70) | CXCR2CXCR1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383488-A2 | METHODS OF SYNTHESIZING PHENOL-CONTAINING COMPOUNDS | SmithKline Beecham Corporation (US) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002079122-A2 | METHODS OF SYNTHESIZING PHENOL-CONTAINING COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-10-10 | — | — | WO | disclosed |