SCHEMBL6550093

SCHEMBL6550093

O=C(Nc1ccccc1)c1c(Cl)ccc([N+](=O)[O-])c1Cl

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 9/20 0.57
KMT2A Q03164 9/20 0.57
MAPT P10636 4/20 0.57
GAA P10253 3/20 0.57
LMNA P02545 2/20 0.57
HTT P42858 1/20 0.57
CYP3A4 P08684 2/20 0.56
TSHR P16473 2/20 0.56
TP53 P04637 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56
PKM P14618 1/20 0.56
NFKB1 P19838 1/20 0.56
MAPK1 P28482 1/20 0.56
CYP2C19 P33261 1/20 0.56
PPARG P37231 1/20 0.56
THPO P40225 1/20 0.56
MTOR P42345 1/20 0.56
RORC P51449 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6550860 0.87 MEN1 (0.56) MEN1KMT2AMAPTGAALMNA
SCHEMBL14638518 0.86 MEN1 (0.56) MEN1KMT2AMAPTGAALMNA
SCHEMBL14649317 0.86 MEN1 (0.55) MEN1KMT2AMAPTGAALMNA
SCHEMBL3515462 0.86 TYK2 (0.58) MEN1KMT2AMAPTGAALMNA
SCHEMBL28316737 0.86 MEN1 (0.48) MEN1KMT2AMAPTGAALMNA
SCHEMBL22081714 0.84 DHODH (0.54) MEN1KMT2AMAPTGAALMNA
SCHEMBL6549682 0.83 CXCR2 (0.55) MEN1KMT2AMAPTGAALMNA
SCHEMBL4045541 0.78 MEN1 (0.65) MEN1KMT2AMAPTGAALMNA
SCHEMBL912772 0.78 TDP1 (0.60) MEN1KMT2AMAPTGAALMNA
SCHEMBL1455286 0.77 KMT2A (0.90) MEN1KMT2AMAPTGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118044519-A Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-05-17 CN disclosed
CN-110072842-B Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-02-02 CN disclosed
US-20040110954-A1 Methods of synthesizing phenol-contining compounds SMITHKLINE BEECHAM CORPORATION 2004-06-10 US disclosed
EP-1383488-A2 METHODS OF SYNTHESIZING PHENOL-CONTAINING COMPOUNDS SmithKline Beecham Corporation (US) 2004-01-28 EP disclosed
WO-2002079122-A2 METHODS OF SYNTHESIZING PHENOL-CONTAINING COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 2002-10-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110954-A1 Methods of synthesizing phenol-contining compounds COMT, BPHL, PNMT MEN1 2475/4885KMT2A 1488/4885MAPT 2532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.