SCHEMBL6549689

SCHEMBL6549689

Fc1ccc2c(c1F)c1c(F)c(F)c(F)c(F)c1c1c(F)c(F)c(F)c(F)c21

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.34
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7941915 0.90 GPR84 (0.32) GPR84CES2CES1
SCHEMBL31317752 0.83 GPR84 (0.34) GPR84CES2CES1
SCHEMBL31711770 0.83 GPR84 (0.34) GPR84CES2CES1
SCHEMBL2497509 0.83 GPR84 (0.34) GPR84CES2CES1
SCHEMBL31711745 0.80 HPRT1 (0.33) GPR84
SCHEMBL18291088 0.79 GPR84 (0.32) GPR84CES2CES1
SCHEMBL31711763 0.76
SCHEMBL5609948 0.75 CES2 (0.32) GPR84CES2CES1
SCHEMBL21011329 0.75 GPR84 (0.31) GPR84
SCHEMBL20356020 0.74 GPR84 (0.35) GPR84CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1290002-B1 CHEMICAL PRODUCTS SUITED FOR USE AS CO-CATALYSTS, METHOD FOR THE PREPARATION THEREOF AND THEIR USE IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS BASELL POLYOLEFINE GMBH (DE) 2004-01-21 EP disclosed
EP-1290002-A1 CHEMICAL PRODUCTS SUITED FOR USE AS CO-CATALYSTS, METHOD FOR THE PREPARATION THEREOF AND THEIR USE IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS Basell Polyolefine GmbH (DE) 2003-03-12 EP disclosed
WO-2001090112-A1 CHEMICAL PRODUCTS SUITED FOR USE AS CO-CATALYSTS, METHOD FOR THE PREPARATION THEREOF AND THEIR USE IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS BASELL POLYOLEFINE GMBH (DE) 2001-11-29 WO disclosed