SCHEMBL6549798

SCHEMBL6549798

ClC(Cl)=CCOc1cc(Cl)c(OCCCOc2ccc(C=NOCc3ccccc3)cc2)c(Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.48
KMT2A Q03164 5/20 0.48
L3MBTL1 Q9Y468 5/20 0.48
MAPT P10636 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
PPARG P37231 4/20 0.42
PPARA Q07869 4/20 0.42
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
NPC1 O15118 4/20 0.38
RAB9A P51151 4/20 0.38
SMN1; SMN2 Q16637 4/20 0.38
GAA P10253 3/20 0.38
POLB P06746 1/20 0.38
ADCYAP1R1 P41586 1/20 0.38
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 2/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6549794 1.00 MEN1 (0.48) MEN1KMT2AL3MBTL1MAPTTDP1
SCHEMBL6550005 0.90 MEN1 (0.41) MEN1KMT2AL3MBTL1MAPTTDP1
SCHEMBL6549999 0.90 MEN1 (0.41) MEN1KMT2AL3MBTL1MAPTTDP1
SCHEMBL6547739 0.90 PPARG (0.43) MEN1KMT2AL3MBTL1MAPTTDP1
SCHEMBL6547748 0.90 PPARG (0.43) MEN1KMT2AL3MBTL1MAPTTDP1
SCHEMBL6548216 0.89 L3MBTL1 (0.43) MEN1KMT2AL3MBTL1MAPTTDP1
SCHEMBL6548218 0.89 L3MBTL1 (0.43) MEN1KMT2AL3MBTL1MAPTTDP1
SCHEMBL6547921 0.87 L3MBTL1 (0.43) MEN1KMT2AL3MBTL1MAPTTDP1
SCHEMBL6547917 0.87 L3MBTL1 (0.43) MEN1KMT2AL3MBTL1MAPTTDP1
SCHEMBL6548576 0.87 UNG (0.37) MEN1KMT2AL3MBTL1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed
EP-0975586-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION Sumitomo Chemical Company, Limited (JP) 2000-02-02 EP disclosed
WO-1998045254-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 MEN1 4425/4885KMT2A 2985/4885L3MBTL1 876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.