Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28513225 | 0.82 | ALDH1A1 (0.47) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL1059869 | 0.75 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL2701449 | 0.72 | ALDH1A1 (0.59) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL21450709 | 0.68 | PARP1 (0.63) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL1984717 | 0.66 | ALDH1A1 (0.40) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL8650891 | 0.66 | ALDH1A1 (0.54) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL4590391 | 0.65 | ALDH1A1 (0.60) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL6418458 | 0.64 | ALDH1A1 (0.40) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL16800740 | 0.64 | ALDH1A1 (0.48) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 | |
| SCHEMBL7645364 | 0.64 | ALDH1A1 (0.44) | ALDH1A1HSD17B10TSHRHPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383810-A2 | GAS PHASE PROCESS FOR POLYMERS WITH GROUP 4 METAL COMPLEX CATALYST ADDITION | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002077045-A2 | GAS PHASE PROCESS FOR POLYMERS WITH GROUP 4 METAL COMPLEX CATALYST ADDITION | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2002-10-03 | — | — | WO | disclosed |