SCHEMBL6549880

SCHEMBL6549880

C=COC(=O)OC1(C(=O)c2ccccc2)CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.35
LMNA P02545 2/20 0.35
KMT2A Q03164 3/20 0.34
ALDH1A1 P00352 2/20 0.34
MEN1 O00255 2/20 0.34
POLB P06746 1/20 0.34
CTSK P43235 2/20 0.33
AKR1C1 Q04828 1/20 0.33
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
HDAC4 P56524 1/20 0.32
HPGD P15428 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ADRB2 P07550 1/20 0.32
CTSL P07711 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8383354 0.82 AKT1 (0.41) AKT1LMNAKMT2AALDH1A1MEN1
SCHEMBL16668009 0.80 LMNA (0.41) LMNAKMT2AALDH1A1MEN1CTSK
SCHEMBL16576959 0.77 LMNA (0.39) LMNAALDH1A1CTSKAKR1C1CYP3A4
SCHEMBL26110622 0.77 ALDH1A1 (0.41) LMNAKMT2AALDH1A1POLBAKR1C1
SCHEMBL1442824 0.75 ELANE (0.47) LMNAKMT2AALDH1A1MEN1POLB
SCHEMBL3318244 0.75 LMNA (0.40) LMNAKMT2AALDH1A1MEN1CTSK
SCHEMBL28288379 0.74 LMNA (0.39) LMNAKMT2AALDH1A1POLBCTSK
SCHEMBL17051295 0.74 LMNA (0.39) LMNAALDH1A1CTSKCYP3A4TSHR
SCHEMBL10384827 0.73 ALDH1A1 (0.43) LMNAKMT2AALDH1A1CTSKAKR1C1
SCHEMBL28356588 0.73 MAPT (0.46) LMNAKMT2AALDH1A1MEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1135219-B1 METHOD FOR PRODUCING ADHESIVE SURFACE COATINGS CIBA SC HOLDING AG (CH) 2004-01-28 EP disclosed
US-6548121-B1 Subjecting substrate to action of low-temperature plasma discharge or radiation, applying photoinitiator containing ethylenically unsaturated group, curing, depositing metal or oxide CIBA SPECIALTY CHEMICALS CORPORATION 2003-04-15 US disclosed
EP-1135219-A1 METHOD FOR PRODUCING ADHESIVE SURFACE COATINGS Ciba SC Holding AG (CH) 2001-09-26 EP disclosed
WO-2000024527-A1 METHOD FOR PRODUCING ADHESIVE SURFACE COATINGS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-05-04 WO disclosed