SCHEMBL6549914

SCHEMBL6549914

CCCCCCCC/C=N/OCCCCOc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRB P10828 8/20 0.35
S1PR2 O95136 1/20 0.35
S1PR1 P21453 1/20 0.35
S1PR3 Q99500 1/20 0.35
LPAR2 Q9HBW0 1/20 0.35
GALK1 P51570 1/20 0.34
PLA2G2A P14555 1/20 0.32
PSEN1 P49768 2/20 0.32
PSEN2 P49810 2/20 0.32
APH1B Q8WW43 2/20 0.32
NCSTN Q92542 2/20 0.32
APH1A Q96BI3 2/20 0.32
PSENEN Q9NZ42 2/20 0.32
THRA P10827 2/20 0.32
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6548586 1.00 THRB (0.35) THRBS1PR2S1PR1S1PR3LPAR2
SCHEMBL6548588 1.00 THRB (0.35) THRBS1PR2S1PR1S1PR3LPAR2
SCHEMBL6547899 1.00 THRB (0.35) THRBS1PR2S1PR1S1PR3LPAR2
SCHEMBL6548228 1.00 THRB (0.35) THRBS1PR2S1PR1S1PR3LPAR2
SCHEMBL6549281 1.00 THRB (0.35) THRBS1PR2S1PR1S1PR3LPAR2
SCHEMBL6550014 1.00 THRB (0.35) THRBS1PR2S1PR1S1PR3LPAR2
SCHEMBL6547896 1.00 THRB (0.35) THRBS1PR2S1PR1S1PR3LPAR2
SCHEMBL6549931 1.00 THRB (0.35) THRBS1PR2S1PR1S1PR3LPAR2
SCHEMBL6548231 1.00 THRB (0.35) THRBS1PR2S1PR1S1PR3LPAR2
SCHEMBL6548954 0.99 GALK1 (0.34) THRBS1PR2S1PR1S1PR3LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 THRB 1780/4885S1PR2 2362/4885S1PR1 2205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.