SCHEMBL6550150

SCHEMBL6550150

[CH2]C(C)(C)[SiH2]OCCCC

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.35
ADRB1 P08588 1/20 0.35
ADRB3 P13945 1/20 0.35
TSHR P16473 2/20 0.31
CYP3A4 P08684 1/20 0.31
HPGD P15428 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL704253 0.80 ADRB2 (0.38) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL6303863 0.78 ADRB2 (0.36) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL27930944 0.76 TSHR (0.35) ADRB2ADRB1ADRB3TSHRHPGD
SCHEMBL23093206 0.73 ADRB2 (0.32) ADRB2ADRB1ADRB3
SCHEMBL8667749 0.73 TSHR (0.43) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL9410812 0.71 THRB (0.38) TSHR
SCHEMBL6687927 0.69 SMPD1 (0.34) TSHR
SCHEMBL8668498 0.68 TSHR (0.43) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL705064 0.68 ADRB2 (0.45) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL133600 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1385905-A1 PRODUCT IN SUBDIVIDED FORM FOR PREPARING CROSSLINKABLE ELASTOMERIC COMPOSITIONS PIRELLI PNEUMATICI S.p.A. (IT) 2004-02-04 EP disclosed
WO-2002083783-A1 PRODUCT IN SUBDIVIDED FORM FOR PREPARING CROSSLINKABLE ELASTOMERIC COMPOSITIONS PIRELLI PNEUMATICI S.P.A. (IT) 2002-10-24 WO disclosed