SCHEMBL6550319

SCHEMBL6550319

CO[Si]([CH]C(C)C)(OC)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
CA4 P22748 1/20 0.31
PDE4A P27815 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL143426 0.74 ALDH1A1 (0.33) CA4
SCHEMBL18638324 0.74 CA4 (0.39) MEN1KMT2ATAAR1CA4
SCHEMBL28498809 0.72 ALDH1A1 (0.32) CA4
SCHEMBL28421127 0.69 ALDH1A1 (0.30) CA4
SCHEMBL27710309 0.69 MAOB (0.44) MEN1KMT2A
SCHEMBL704038 0.69 CA4 (0.36) MEN1KMT2ACA4PDE4APDE4B
SCHEMBL645565 0.67 CA4 (0.35) KMT2ACA4
SCHEMBL14841766 0.67 ESR1 (0.37) KMT2ACA4
SCHEMBL703676 0.67 POLB (0.35) MEN1KMT2ACA4
SCHEMBL647414 0.67 CA4 (0.35) KMT2ACA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1385905-A1 PRODUCT IN SUBDIVIDED FORM FOR PREPARING CROSSLINKABLE ELASTOMERIC COMPOSITIONS PIRELLI PNEUMATICI S.p.A. (IT) 2004-02-04 EP disclosed
EP-1339539-A1 PROCESS FOR MANUFACTURING, MOULDING AND CURING TYRES FOR VEHICLES WHEELS PIRELLI PNEUMATICI Società per Azioni (IT) 2003-09-03 EP disclosed
EP-0794186-B1 The preparation of sulfur-containing organosilicon compounds GOODYEAR TIRE & RUBBER (US) 2003-05-28 EP disclosed
WO-2002083783-A1 PRODUCT IN SUBDIVIDED FORM FOR PREPARING CROSSLINKABLE ELASTOMERIC COMPOSITIONS PIRELLI PNEUMATICI S.P.A. (IT) 2002-10-24 WO disclosed
WO-2002045942-A1 PROCESS FOR MANUFACTURING, MOULDING AND CURING TYRES FOR VEHICLES WHEELS PIRELLI PNEUMATICI S.P.A (IT) 2002-06-13 WO disclosed