SCHEMBL28498809

SCHEMBL28498809

CC=C[Si](OC)(OC)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32
CA4 P22748 1/20 0.32
MAPT P10636 1/20 0.32
TRPA1 O75762 1/20 0.31
NFE2L2 Q16236 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27710309 0.79 MAOB (0.44) ALDH1A1CYP1A2MAPTTRPA1NFE2L2
SCHEMBL28421127 0.79 ALDH1A1 (0.30) ALDH1A1CYP1A2CYP2C19CA4
SCHEMBL30991843 0.78 ALDH1A1 (0.32) ALDH1A1CYP1A2CYP2C19CA4MAPT
SCHEMBL28494051 0.78 MAPT (0.33) MAPT
SCHEMBL15662423 0.76 MAPT (0.42) ALDH1A1MAPTESR1
SCHEMBL18638324 0.76 CA4 (0.39) ALDH1A1CYP1A2CYP2C19CA4MAPT
SCHEMBL143426 0.76 ALDH1A1 (0.33) ALDH1A1CA4TRPA1NFE2L2ESR1
SCHEMBL28904117 0.75 LMNA (0.33) ALDH1A1MAPT
SCHEMBL18610644 0.73 MAPT (0.37) MAPTESR1ESR2
SCHEMBL6550319 0.72 MEN1 (0.32) CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115181223-B Low-gloss matte auxiliary agent, preparation method thereof and molded body 铨盛聚碳科技股份有限公司 2023-08-29 CN claimed
CN-115181223-B Low-gloss matte auxiliary agent, preparation method thereof and molded body 铨盛聚碳科技股份有限公司 2023-08-29 CN disclosed
CN-115181223-A Low-gloss matte auxiliary agent, preparation method thereof and formed body 铨盛聚碳科技股份有限公司 2022-10-14 CN disclosed
CN-114085382-A Hydrogen-containing poly titanium boron siloxane flame retardant, and preparation method and application thereof 铨盛聚碳科技股份有限公司 2022-02-25 CN disclosed
CN-112094414-B Preparation method of novel liquid silicon carbide ceramic precursor 宁波曙翔新材料股份有限公司 2022-01-07 CN disclosed
CN-112094414-A Preparation method of novel liquid silicon carbide ceramic precursor 宁波曙翔新材料股份有限公司 2020-12-18 CN disclosed